Postoperative analgesic efficacy of ultrasound-guided bilateral transversus abdominis plane block combined with intrathecal morphine injection in patients receiving laparoscopic donor hepatectomy; a randomized controlled trial
Not Applicable
Recruiting
- Conditions
- Factors influencing health status and contact with health services
- Registration Number
- KCT0008406
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients who undergo laparoscopic living donor liver resection
ASA physical status I or II
Exclusion Criteria
ASA physical status III or more
Pregnancy
Severe impaired coagulation profile (equal or more than INR 1.5 last coagulation test before the surgery)
Pathients who have systemic infection or local infection on lumbar
Chronic pain patients
Patients who don'r understand about study or refuse the study
Patients allergic to local anesthetics
Patients who have history of severe psychological disease
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Peak pain score (Numeric rating scale 0-10) in PAC
- Secondary Outcome Measures
Name Time Method Pain score (Numeric rating scale 0-10);Pain score (Numeric rating scale 0-10);Opioid consumption after the surgery;Satisfaction of sleep after the surgery ;Satisfaction of pain relief;complication associated with the procedure ;The Korean version of questionnaire of QoR-15 score before and after the surgery;nausea, vomiting, itching after the surgery
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the synergistic analgesic effect of ultrasound-guided bilateral TAP block and intrathecal morphine in laparoscopic donor hepatectomy?
How does the combination of ultrasound-guided TAP block and intrathecal morphine compare to standard multimodal analgesia in post-laparoscopic hepatectomy pain control?
Which biomarkers correlate with improved analgesic outcomes in patients receiving combined TAP block and intrathecal morphine after laparoscopic donor hepatectomy?
What are the incidence and management strategies for opioid-related adverse events in the combined TAP block and intrathecal morphine protocol for hepatectomy patients?
Are there alternative local anesthetic agents or adjuvants that enhance the efficacy of ultrasound-guided TAP block when paired with intrathecal morphine in abdominal surgery?