ong-term follow-up of children exposed in utero to low-dose aspirin for prevention of preterm birth, a follow-up of the APRIL trial
Recruiting
- Conditions
- Prevention of preterm birth in multiple pregnancy
- Registration Number
- NL-OMON21183
- Lead Sponsor
- Amsterdam UMC
- Brief Summary
n/a
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
All mothers and their child that participated in the APRIL trial. Mortality data of all children up to 4 years will be collected. Surviving children will be assessed at 4 years corrected age (ranging between 45 months and 51 months calculated from the expected date of delivery).
Exclusion Criteria
Women that withdraw their consent after randomization in the original APRIL trial. Women that did not gave consent to be approached for follow-up during the original APRIL trial.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method (neuro)development and behaviour
- Secondary Outcome Measures
Name Time Method Mortality (perinatal death and infant death up to 4 years of age), child’s growth and health related problems (i.e. information on surgery, medication use and hospital admissions).