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Clinical Trials/NCT00804817
NCT00804817
Completed
Not Applicable

Somatic-psychosocial Multidisciplinary Care Concept for Oncologic Patients Undergoing Hematopoietic Stem Cell Transplantation (HSCT): a Prospective Non-randomized Clinical Trial

Martin-Luther-Universität Halle-Wittenberg1 site in 1 country84 target enrollmentDecember 2007

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Oral Mucositis
Sponsor
Martin-Luther-Universität Halle-Wittenberg
Enrollment
84
Locations
1
Primary Endpoint
Health Related Quality of Life (HRQoL)
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

This study will test the SCION (Self care improvement through oncology nursing)-HSCT program a multi-modular, somatic-psycho-social care intervention to improve self management in oncologic patients undergoing HSCT. The study will determine if the self management skills of the patients to enhance:

  • physical activity,
  • prevention of oral mucositis and
  • mal nutrition during the period of hospitalization.

It is hypothesized that patients who receive the multi-modular somatic-psycho-social care intervention will have better health related quality of life (HRQoL).

Detailed Description

According to Precede Model of health behavior from Green - modified by our research group - patients self management skills are affected by the patients' knowledge, activities and attitude to self management. Therefore, we propose a prospective non-randomized clinical trial that will test the effectiveness of SCION-HSCT program against care as usual on perceived HRQoL of the patient and the adherence to care program. Oncology patients with HSCT will be recruited by the nurses of the participating wards under the guidance of a research nurse. They will be included in the trial if they will meet the inclusion criteria and signed informed consent (the full inclusion criteria see below). Groups will be treated consecutively. The first group will receive care as usual (Control). After finishing the control period, i.e. after 42 Patients will have completed the trial. The the newly assigned patients will be treated according to SCION-HSCT program a multi-modular somatic-psycho-social care intervention (Intervention). The intervention will be conducted by specially trained ward nurses in cooperation with the research nurse. It includes components of knowledge, skills training, and coaching to improve patients adherence to self management strategies for physical activity, prevention of oral mucositis and mal nutrition prevention. The HRQoL, adherence and symptom level of the patients will be observed up to 100 days post HSCT. Both quantitative and qualitative analyses will be conducted to evaluate patient outcomes.

Registry
clinicaltrials.gov
Start Date
December 2007
End Date
August 2010
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Hematologic Patients (\> 14 years of age)
  • Hematological stem cell transplantation (HSCT) allogenic or autologous
  • Informed consent

Exclusion Criteria

  • Unable to read, write, and understand German

Outcomes

Primary Outcomes

Health Related Quality of Life (HRQoL)

Time Frame: day before discharge from hospital

Secondary Outcomes

  • Physical Fitness (Step-Test)(day before discharge from hospital)
  • Fatigue (Fatigue Symptom Inventory - D (German))(day before discharge from hospital)
  • Physical Resources (German Conservation of Resources Evaluation (GCOR))(day before discharge from hospital)
  • Symptom experience (Common Terminology Criteria for adverse events - CTCAE v. 3.0)(day before discharge from hospital)

Study Sites (1)

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