EFFECT OF EPIDURAL STEROID INJECTION ON HYPOTHALMIC PITUTARY AXIS
Not Applicable
- Conditions
- Health Condition 1: null- chronic low back ache
- Registration Number
- CTRI/2018/04/013454
- Lead Sponsor
- SRI GURU RAM DAS INSTITUTE OF MEDICAL SCIENCES AND RESEARCH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
PATIENTS WITH LOW BACK ACHE DUE TO DISC HERNIATION, ANNULAR TEAR, SPINAL STENOSIS.
Exclusion Criteria
1. PAIN RELIEVED BY ORAL MEDICATION.
2. PATIENTS WHO DO NOT GIVE CONSENT FOR EPIDURAL STEROID INJECTION AND WHO DONT AGREE TO GIVE BLOOD SAMPLES.
3. KNOWN HISTORY OF ALLERGY TO LOCAL ANESTHETIC
PSYCHIATRIC HISTORY OR OTHER CONCOMITANT DISEASE WHICH MAY LEAD TO UNRELIABILITY.
4. PREGNANCY
5. CONTRAINDICATION TO EPIDURAL ANESTHESIA LIKE LOCAL INFECTION/ GENERALISED SEPTICEMIA/ PLATELET AND CLOTTING FACTOR ABNORMALITY, SIGNIFICANT NEUROLOGICAL DISEASE WITH MOTOR AND SENSORY DEFICIT, DIAGNOSED INCREASED INTRACRANIAL PRESSURE.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method CHANGES IN PLASMA CORTISOL AND ACTH LEVELS COMPARED TO BASELINETimepoint: CHANGES IN PLASMA CORTISOL AND ACTH LEVELS AT BASELINE, AND 2, 4, 12 WEEKS POST EPIDURAL STEROID INJECTION.
- Secondary Outcome Measures
Name Time Method CORRELATION OD PLASMA CORTISOL WITH PERCENTAGE IMPROVEMENTTimepoint: 2,4,12 WEEKS