NCT02740894已完成不适用
Can Epidermal Growth Factor Receptor - Tyrosine Kinase Inhibitor Improve the Postoperative Survivorship for Inoperable Non-small Cell Lung Cancer With Spinal Metastasis of the Thoracic and Lumbar Spine?- A Retrospective Comparison With Platinum-based Chemotherapy
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 主要终点
- Survival and neurologic outcome of 60 participants receiving targeted therapy for nonsmall cell lung cancer with spinal metastaasis. Neurological outcome by Frankel grading and ambulation status.
研究概览
简要总结
Not significantly increased survival in T/T
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •NSCLC with spinal metastasis
排除标准
- •brain metastasis and expected survival < 3 months
研究组 & 干预措施
targeted therapy
according to national healthy policy, targeted therapy is the optional therapy
干预措施: Gefitinib (Drug)
traditional chemotherapy
according to national healthy policy, chemotherapy is the first line treatment.
干预措施: Gefitinib (Drug)
结局指标
主要结局
Survival and neurologic outcome of 60 participants receiving targeted therapy for nonsmall cell lung cancer with spinal metastaasis. Neurological outcome by Frankel grading and ambulation status.
时间窗: postoperation to mortality, up to 2 year
次要结局
未报告次要终点
研究者
vghtpe user
ST Wang, Chief of spinal surgery. Taipei Veterans General Hospital, Taiwan
Taipei Veterans General Hospital, Taiwan
相似试验
已完成
不适用
Real-world Analysis of Workup at Disease Progression and Implementation of Osimertinib for EGFR+ NSCLCEGFR Positive Non-small Cell Lung CancerNCT04105153Thoraxklinik-Heidelberg gGmbH400
Unknown
2 期
Continuation of TKI With or Without Chemotherapy Beyond Gradual ProgressionNon Small Cell Lung CancerNCT01998061Zhejiang University20
招募中
2 期
Tyrosine Kinase Inhibitors in Metastastic Adenoid Cystic CarcinomaCarcinoma, Adenoid CysticNCT04974866Qingdao Central Hospital20
已完成
不适用
A Study of Serum Protein Profiling in Patients With Non-Small Cell Lung Cancer Treated With Gefitinib or ErlotinibNon Small Cell Lung CancerNCT00717847National University Hospital, Singapore
已完成
不适用
Understanding and Overcoming the Early Adaptive Resistance to EGFR Tyrosine-kinase Inhibitors in Lung Cancer PatientsLung Cancer, Nonsmall CellNCT04222335University Hospital, Toulouse47