The effect of haemoadsorption in relation to the cytokine concentration during cardiothoracic surgery procedures while using extracorporeal circulation.
Completed
- Conditions
- Produktie van cytokine door het lichaam tijdens open hartchirurgie.Cytokine productionInflammatory reactions10011082
- Registration Number
- NL-OMON45517
- Lead Sponsor
- Medisch Centrum Leeuwarden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Elective CABG
Signed informed consend
age >18 years, <75 years
Exclusion Criteria
Emergency surgery
Combined surgical intervention
Coagulation disorders
Low platelet count <100*109/l
Hb:< 7,5 mmol/l, calculated Ht <20 % after hemodilution
Serum creatinine of more than 2x reference value (110 µmol/l)
Severe COPD
Long-term therapy with corticosteroids or Immunosuppressive therapy
Participation in another clinical intervention trial
CRP >5 mg/l
Patients that are Heparin Induced Thrombocytopenia (HIT) positive and citrate regional anticoagulation is unavailable as an alternative anticoagulation method.
Hypersensitive / allergic reaction to: polystyreen/divinylbenzeen, polycarbonaat, polypropyleen, siliconen en polyester
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method