Evaluating Taste and Smell Function and Food and Taste Preferences of Head and Neck Cancer Patients During Radiation Therapy/Chemotherapy
Completed
- Conditions
- Head and Neck Cancer
- Registration Number
- NCT00375921
- Lead Sponsor
- AHS Cancer Control Alberta
- Brief Summary
Changes to taste and smell have been reported in head and neck cancer patients who undergo radiation and chemotherapy. This may cause food to be unappealing and can lead to a reduced food intake. Thsi study will increase our understanding of taste and smell changes and how it relates to food and taste preferences.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- 18 years or older
- diagnosed with head and neck cancer including the lip, oral cavity, salivary glands, paranasal sinuses, oropharynx, hypopharynx, larynx and thyroid
- all histologic types of cancer
- all tumour stages according to American Joint Committee for Cancer (AJCC) Staging
- all forms of RT including standard or investigational and/or concurrent standard or investigational chemotherapy for head and neck cancers
- alert and mentally competent
- English speaking
Exclusion Criteria
- unable to swallow
- unwilling to participate
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link radiation/chemotherapy to taste/smell dysfunction in head and neck cancer patients?
How do taste/smell alterations in NCT00375921 compare to standard-of-care treatment effects in head and neck cancer?
Which biomarkers correlate with taste preference changes in head and neck cancer patients post-chemoradiation?
What adverse events related to chemosensory function are reported in head and neck cancer trials using radiation/chemotherapy?
Are there adjuvant therapies or compounds that mitigate taste/smell loss in head and neck cancer patients undergoing NCT00375921 protocols?
Trial Locations
- Locations (1)
Cross Cancer Institute
🇨🇦Edmonton, Alberta, Canada
Cross Cancer Institute🇨🇦Edmonton, Alberta, Canada