临床试验/NCT06418165

NCT06418165招募中不适用

Vienna Hypothermic Oxygenated Machine Perfusion for Liver Transplantation Study

Medical University of Vienna1 个研究点分布在 1 个国家目标入组 500 人开始时间: 2018年1月1日最近更新: 2024年5月17日

适应症

试验速览

阶段: 不适用
状态: 招募中
发起方: Medical University of Vienna
入组人数: 500
试验地点: 1
主要终点: Incidence of ischemic-type biliary lesions

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

In this observational cohort study data on all patients undergoing liver transplantation after hypothermic oxygenated machine perfusion at Medical University of Vienna will be prospectively recorded. Investigation of short- and long-term outcome in this cohort will be conducted.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•patients undergoing liver transplantation with the use of hypothermic oxygenated machine perfusion
•age ≥ 18 years

排除标准

•pregnancy
•partial grafts
•the anatomical integrity of the liver is not preserved in a way that makes the perfusion of the liver possible

结局指标

主要结局

Incidence of ischemic-type biliary lesions

时间窗: Within one year after liver transplantation

Non-anastomotic stenosis, post-transplant cholangiopathy

次要结局

Incidence of re-transplantation(Evaluated in the immediate postoperative period, specifically within the first postoperative week)
Rate of early allograft dysfunction(Evaluated within the first 7 postoperative days)
Rate of primary non-function(Evaluated in the immediate postoperative period, specifically within the first postoperative week)

研究者

发起方

Medical University of Vienna

申办方类型

Other

责任方

Principal Investigator

主要研究者

David Pereyra

Principal Investigator

Medical University of Vienna

研究点 (1)

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