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the effect of oral isotretinoin on the nasal and oral bacteria in patients with acne

Early Phase 1
Conditions
acne vulgaris.
Acne vulgaris
Registration Number
IRCT2016120427636N4
Lead Sponsor
Vice Chancellor for Research of Mazandaran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

1. Patients with moderate to severe acne candidates for systemic isotretinoin therapy.;consent to participate in the study
Exclusion criteria: Patients who are pregnant or lactating women;topical or systemic anti-acne drugs or antibiotics were used a month prior to or in conjunction with study.; Patients have been affected with infectious and respiratory diseases a month before o during the study.; Patients with chronic liver disease or peptic ulcer 5-consumers of drugs that cause acne include: vitamin B12, topical steroids or systemic anti-TB drugs, lithium, azathioprine, carbamazepine and phenytoin;patients with Hematologic disorders (according hematologic side effects of treatment)

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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