NCT04539288已完成不适用
Pregnancy to Postpartum Transition of Serum Biomarkers in Women With Gestational Diabetes
First Affiliated Hospital, Sun Yat-Sen University1 个研究点 分布在 1 个国家目标入组 3,099 人开始时间: 2013年5月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 3,099
- 试验地点
- 1
- 主要终点
- T2DM
研究概览
简要总结
Gestational diabetes mellitus (GDM) is commonly linked to the development of type 2 diabetes mellitus (T2DM). There is a need to characterize metabolic changes associated with GDM in order to find novel biomarkers for T2DM.
详细描述
GDM, a common complication of pregnancy, affects 17.8% of pregnancies worldwide per year. Women with a history of GDM have an approximately 7-fold higher risk for developing T2DM in the future than women without GDM. However, data on the factors associated with the development of T2DM in women with GDM are not widely available.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women who were dignosed GDM.
- •Women with singleton pregnancy.
- •Give birth in the First Affiliated Hospital in Sun Yat-sen University.
排除标准
- •Women who were diagnosed PGDM.
- •Younger than 18 years old.
- •Older than 45 years old.
- •Multiple pregnancy.
- •Diagnosed DM before.
- •Complicationg other diseases, like hypertension, thyroid diseases, etc.
- •Taking any drug affect glucose and lipid metabolism.
结局指标
主要结局
T2DM
时间窗: 4-6 weeks.
Women with GDM develop T2DM in postpartum.
次要结局
- IGT(4-6 weeks.)
研究者
Dongyu Wang
Principal Investigator
First Affiliated Hospital, Sun Yat-Sen University
研究点 (1)
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