MedPath

Brexpiprazole for the long-term treatment of patients with agitation associated with dementia of the Alzheimer's type

Phase 3
Completed
Conditions
Agitation Associated With Dementia of the Alzheimer's Type
Registration Number
JPRN-jRCT2080224118
Lead Sponsor
Otsuka Pharmaceutical Co., Ltd.
Brief Summary

Brexpiprazole administered at doses of 1 mg and 2 mg once daily for 14 weeks in patients with agitation associated with dementia of the Alzheimer`s type who completed the 10-week treatment period of Trial 331-102-00088 provided sustained therapeutic effect and was well tolerated with no outcomes suggestive of a significant impact on safety.

Detailed Description

Not available

Recruitment & Eligibility

Status
completed
Sex
All
Target Recruitment
164
Inclusion Criteria

1. Patients who completed the double-blind treatment period for 10 weeks and all observation, examination and evaluation at Week 10 of the double-blind trial.
2. Patients whose caregiver can properly collect the necessary information.

Exclusion Criteria

1. Patients who had a serious adverse event which the principal investigator or sub-investigator assessed as related to the investigator product during the double-blind trial.
2. Patients who had delirium during the double-blind trial.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath