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Clinical Trials/NCT04780919
NCT04780919
Completed
N/A

The Ultrasound-Monitored Changes in Achilles Tendinopathy After Focused Extracorporeal Shock Wave Therapy - a Randomized Sham-Controlled Trial

University Hospital, Motol1 site in 1 country18 target enrollmentFebruary 1, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Achilles Tendinopathy
Sponsor
University Hospital, Motol
Enrollment
18
Locations
1
Primary Endpoint
Change of Ankle Dorsiflexion Range of Motion
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This study is designed as a randomized, placebo-controlled clinical trial in which we monitor the effects of low-energy focused extracorporeal shockwave therapy (ESWT) in patients with Achilles tendinopathy (AT). Participants will be randomly divided into two groups. ESWT according to selected parameters will be applied to Group A. Group B will receive sham ESWT.

Patients in both groups will have the same program. The research for one patient lasts a total of 8 weeks (2 months) from the initial to the final examination. In the first week, there will be a clinical examination by a physiotherapist, an ultrasonographic examination, and the patient will complete a VISA-A questionnaire. At the end of the examination, the patient will be randomly assigned to group A or B and receive the first application. For the next 4 weeks, additional applications will be performed once a week. The interval between individual applications should be at least 7 days. Thus, a total of 5 applications of ESWT or sham ESWT will be performed. The final examination will take place 3 weeks after the last application and will include the same procedures as for the initial examination.

Detailed Description

This study is designed as a randomized, placebo-controlled clinical trial in which we monitor the effects of low-energy focused extracorporeal shockwave therapy (ESWT) in patients with Achilles tendinopathy (AT). Participants will be randomly divided into two groups. ESWT according to selected parameters will be applied to Group A. Group B will receive sham ESWT. Patients in both groups will have the same program. The research for one patient lasts a total of 8 weeks (2 months) from the initial to the final examination. In the initial session, there will be a clinical examination by a physiotherapist, which includes case history questions, measuring range of motion (measured by weight-bearing lunge test), functional loading tests (1-leg heel rise test, 1-leg hop test) and an ultrasonographic examination (tendon cross section area and width at the maximal tendon antero-posterior width place). In addition, the patient will complete a VISA-A questionnaire. At the end of the initial session, the patient will be randomly assigned to group A or B and receive the first application. For the next 4 weeks, additional applications will be performed once a week. The interval between individual applications should be at least 7 days. Thus, a total of 5 applications of ESWT or sham ESWT will be performed. The final examination will take place 3 weeks after the last application and will include the same procedures as for the initial examination.

Registry
clinicaltrials.gov
Start Date
February 1, 2021
End Date
April 2, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Motol
Responsible Party
Principal Investigator
Principal Investigator

Stanislav Machač, Ph.D

Academic worker

Charles University, Czech Republic

Eligibility Criteria

Inclusion Criteria

  • the patient complains about Achilles tendon pain, which limits (at least partially) his quality of life during daily activities or sport, and this condition would be referred as a tendinopathy
  • the patient's other leg is asymptomatic
  • the patient is not aware of the symptomatical mechanical tendon damage in past (eg. partial or complete rupture due to injury)
  • the patient has no previous experience with extracorporeal shockwave therapy treatment

Exclusion Criteria

  • the patient has condition which is contraindication for extracorporeal shock wave therapy treatment
  • the patient had symptomatical mechanical tendon damage in past (eg. partial or complete rupture due to injury)

Outcomes

Primary Outcomes

Change of Ankle Dorsiflexion Range of Motion

Time Frame: Change of initial values at 3 weeks follow up after last application (8th week).

Measured using weight-bearing lunge test in cm.

Change in Maximum Pain in the Achilles Tendon Area

Time Frame: Change in maximum pain in the timeframe of the last application (5th week)

Measured by numeric rating scale in points. The values can reach 0-10 points. A higher score means worse pain.

Change in Maximum Pain in the Achilles Tendon Area (Follow up)

Time Frame: Change in maximum pain at 3 weeks follow up after last application (8th week).

Measured by numeric rating scale in points. The values can reach 0-10 points. A higher score means worse pain.

Change in Cross-sectional Area at the Place of Maximum Tendon Width

Time Frame: Change of initial values at 3 weeks follow up after last application (8th week).

Measured by measuring tools in ultrasound machine in cm2. In linear view is selected maximal width place, then the position of ultrasound head is rotated to horizontal view and in this view cross section area is measured.

Secondary Outcomes

  • Number of Participants With Hypoechogenic Areas(Change of the echostructure at 3 weeks follow up after last application (8th week).)
  • Number of Participants With Increased Thickness of Achilles Tendon(Change of the tendon continuity at 3 weeks follow up after last application (8th week).)
  • Change in VISA-A Questionnaire Score(Change of initial values at 3 weeks follow up after last application (8th week).)
  • Change in Single Leg Heel Rise Test(Change of initial values at 3 weeks follow up after last application (8th week))
  • Change in Single Leg Hop Test(Change of initial values at 3 weeks follow up after last application (8th week).)

Study Sites (1)

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