Repetitive Trans-cranial Magnetic Stimulation of the Motor Cortex in Fibromyalgia: A Prospective Randomized Blinded Placebo-controlled Study Evaluating the Clinical Efficiency and the Metabolic Correlate in 18FDG-PET

Assistance Publique Hopitaux De Marseille1 site in 1 country38 target enrollmentOctober 2008

ConditionsFibromyalgia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Fibromyalgia
Sponsor: Assistance Publique Hopitaux De Marseille
Enrollment: 38
Locations: 1
Primary Endpoint: Analgesic efficiency
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Fibromyalgia (FM) syndrome is a chronic pain condition.Repetitive trans-cranial magnetic stimulation (rTMS) was thus suggested in this indication.

Detailed Description

We recently demonstrated that these patients exhibit significant perfusion abnormalities in regions of the brain known to be involved in sensory and affective-attentional dimensions of pain processing. These results, in agreement with previous functional magnetic resonance imaging reports, confirm the hypothesis of central sensitization, which provides the rationale for prescription of centrally acting analgesic agents in patients with severe FM.

Registry

clinicaltrials.gov

Start Date

October 2008

End Date

October 2011

Last Updated

11 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Assistance Publique Hopitaux De Marseille

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Female or male patient, aged from 18 to 65 years
•Patient presenting a primary fibromyalgia answering the criteria of the ACR
•At present painful patient with a digital echelle of the briefing inventory bread superior or equal to 4/10
•Patient presenting a stable treatment since at least 1 less