Nutritional Status, Dietary Patterns, Physical Activity and Adverse Health Outcomes in Adult Survivors of Childhood Cancer
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- The prevalence of sarcopenic obesity in adult survivors of child cancer using DeXA scan
研究概览
简要总结
Childhood cancer survivors also commonly experience obesity, changes in body composition, and metabolic syndrome, which increases their risk of cardiovascular disease. Factors contributing to these issues include the type of cancer treatment received, poor dietary habits, lack of physical activity, and alterations in hormones and inflammation markers.
Despite guidelines recommending healthy lifestyles for cancer survivors, many childhood cancer survivors struggle to adhere to them. However, adopting healthier habits, including better nutrition and increased physical activity, can help prevent or delay the onset of chronic conditions like metabolic syndrome and cardiovascular disease.
Identifying biomarkers and biological mechanisms associated with these conditions could aid in developing prevention strategies. Precise measures of body composition, such as dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis (BIA), are essential for evaluating obesity and its associated risks accurately.
This study aims to investigate sarcopenic obesity prevalence and related factors in adult survivors of childhood cancer at Tata Memorial Hospital (TMH). The hypothesis suggests that Indian survivors may have higher sarcopenic obesity rates and suboptimal dietary and physical activity patterns compared to the general population, leading to adverse metabolic changes.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •All children treated for cancer at Tata Memorial Hospital, Mumbai, are at least 5 years from diagnosis and have completed treatment and are currently in remission for at least 2 years.
- •Those who have received chemotherapy and/or cranial or whole abdominal radiation therapy
- •Currently aged more than 18 years
- •Less than18 years of age at the time of diagnosis and starting treatment
- •Consenting to be included in the study.
排除标准
- •Survivors treated (partially or completely) at centers other than TMH.
- •Survivors whose treatment details are unavailable.
- •Those with severe neurocognitive or physical impairment unable to give accurate response to diet/physical.
- •activity/quality of life assessments.
结局指标
主要结局
The prevalence of sarcopenic obesity in adult survivors of child cancer using DeXA scan
时间窗: The assessments will be conducted after obtaining the consent of the study, in the same visit in After Completion Therapy clinic (ACT Clinic). The standard assessment at each visit and the additional study assessments will be done once after consent is obtained.
次要结局
- 1. The proportion of survivors vs siblings complying with dietary & physical activity(recommendations as laid down by the WCRF/AICR recommendations.)
研究者
Dr Maya Prasad
Tata Memorial Hospital