Effect of EECP on Anterior Ischemic Optic Neuropathy

Not Applicable

• Conditions: Anterior Ischemic Optic Neuropathy
• Interventions: Device: Enhanced external counterpulsation; Drug: Aspirin

• Registration Number: NCT01768260
• Lead Sponsor: First Affiliated Hospital, Sun Yat-Sen University

Brief Summary

Enhanced External Counterpulsation(EECP) therapy may promote the recovery of visual function by improving the blood perfusion of eyes. The present study aims to investigate the effect of EECP on Anterior Ischemic Optic Neuropathy.

Detailed Description

Patients with Anterior Ischemic Optic Neuropathy are randomized into two groups: one group receive standard medical treatment for ischemic optic neuropathy, the other group plus EECP therapy besides standard medical treatment.

Study Timeline

• Study Start: 2012-12
• Study First Submitted: 2013-01-08
• Study First Submitted QC: 2013-01-11
• Study First Posted: 2013-01-15
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-29
• Last Update Posted: 2017-03-31
• Primary Completion: 2017-12
• Study Completion: 2018-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• ischemic optic neuropathy
• within 1 month

Exclusion Criteria

• Hemorrhagic disease
• thrombophlebitis or infection lesions
• severe hypertensive patients
• Atrial fibrillation
• Aortic regurgitation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Enhanced External conterpulsation	Enhanced external counterpulsation	Enhanced external counterpulsation (EECP) is a noninvasive modality for the treatment of ischemic cardiovascular disease. EECP therapy is done by sequential inflation of 3 sets of cuffs wrapped around the lower extremities during diastole and deflation of the cuffs during systole.
aspirin	Aspirin	The subjects with Anterior ischemic Optic Neuropathy received aspirin therapy.
Enhanced External conterpulsation	Aspirin	Enhanced external counterpulsation (EECP) is a noninvasive modality for the treatment of ischemic cardiovascular disease. EECP therapy is done by sequential inflation of 3 sets of cuffs wrapped around the lower extremities during diastole and deflation of the cuffs during systole.

Primary Outcome Measures

Name	Time	Method
visual acuity	7 weeks

Secondary Outcome Measures

Name	Time	Method
Ophthalmic artery blood flow velocity	7 weeks

Trial Locations

Locations (1)

The First Affiliated Hospital of Sun Yat- sen University; 🇨🇳 Guangzhou, Guangdong, China