Testing How Well Magnesium Citrate Capsules Work as Preparation for a Colonoscopy

Not Applicable

Completed

• Conditions: Colonoscopy
• Interventions: Dietary Supplement: Magnesium Citrate Capsules; Other: Polyethylene Glycol 3350; Other: Dulcolax Tablets

• Registration Number: NCT03247595
• Lead Sponsor: LifeBridge Health

Brief Summary

This study compares a colonoscopy preparation composed of magnesium citrate capsules to a preparation of polyethylene glycol solution. The hypothesis is that the magnesium citrate capsules work as well and are better liked by patients due to the lack of taste.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-08-09
• Study First Submitted QC: 2017-08-09
• Study First Posted: 2017-08-11
• Study Start: 2017-09-26
• Primary Completion: 2020-06-16
• Study Completion: 2020-06-16
• Status Verified: 2021-03
• Last Update Submitted: 2021-03-08
• Last Update Posted: 2021-03-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• • Scheduled for colonoscopy at Sinai Hospital or Woodholme GI Associates

Exclusion Criteria

• • Calculated creatinine clearance under 30ml/min

  • On PPI and unable to stop for five days before colonoscopy
  • On H2 blockers and unable to stop for two days before colonoscopy
  • achlorhydria
  • Previous colon surgery
  • Cardiovascular disease, including uncontrolled congestive heart failure, unstable angina pectoris, or recent (3 months) percutaneous transluminal coronary angioplasty, myocardial infarction, or coronary artery bypass graft surgery
  • Colon disease, including chronic constipation (<2 bowel movements per week for >1 year), ileus and/or acute obstruction, ileostomy, right or transverse colostomy, subtotal colectomy (≥50% of colon removed) with ileosigmoidostomy, hypomotility syndrome, megacolon, or idiopathic pseudo-obstruction
  • Pregnant women

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Magnesium Citrate Capsules	Dulcolax Tablets	36 Magnesium citrate capsules
Magnesium Citrate Capsules	Magnesium Citrate Capsules	36 Magnesium citrate capsules
Polyethylene Glycol	Polyethylene Glycol 3350	Polyethylene Glycol 3350: 4 Liters

Primary Outcome Measures

Name	Time	Method
Colon Cleanliness	During colonoscopy	Boston scale rating of colon cleanliness

Secondary Outcome Measures

Name	Time	Method
Patient compliance and satisfaction	On the day of colonoscopy	Patient's experience recorded in a questionnaire

Trial Locations

Locations (2)

Woodholme Gastroenterology; 🇺🇸 Baltimore, Maryland, United States

Sinai Hospital; 🇺🇸 Baltimore, Maryland, United States