Effect of rectal Progesterone on Latent Phase Prolongation in Patients with Preterm Premature Rupture of Membranes
- Conditions
- PPROM.
- Registration Number
- IRCT20200610047716N1
- Lead Sponsor
- Gorgan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 110
Pregnant women 18-45 years
Fetus age between 26-34 weeks based on first trimester of pregnancy ultrasound
PPROM diagnosis based on observation of leakage during speculum examination, nitrazine positive test that these pregnant mothers PPROM without labor pain
Fetus chromosomal abnormalities
Abnormal biophysical profiles less than 4
Intrauterine growth restriction and weight less than ten percent according to the Alexander Growth Standard
Maternal fever greater than 38 ° C
Bleeding after week 24
Chorioamnionitis based on maternal criteria
Type 1 diabetes
Preeclampsia includes high blood pressure and proteinuria after 20 weeks of pregnancy
Cervical discharge and severe obstetric medical diseases
Taking corticosteroids or systemic steroids
Receive antibiotics one week before hospital admission and antibiotic sensitivity
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increased latent phase of labor. Timepoint: From the beginning of the latent phase to the end of the latent phase. Method of measurement: Measurement of latent phase duration based on clinical examination.;Neonatal Apgar score. Timepoint: Apgar score of the first and fifth minutes after birth. Method of measurement: Based on Apgar scoring criteria.
- Secondary Outcome Measures
Name Time Method