Oocyte Cryopreservation

Not Applicable

Terminated

• Conditions: Fertility
• Interventions: Procedure: vitrification of oocytes

• Registration Number: NCT01232972
• Lead Sponsor: Northwell Health

Brief Summary

The purpose of this investigation is to offer the opportunity for young women to cryopreserve (freeze) their oocytes (eggs) for use with IVF at a later point in time.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10
• Study First Submitted: 2010-10-29
• Study First Submitted QC: 2010-11-01
• Study First Posted: 2010-11-02
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Status Verified: 2013-04
• Last Update Submitted: 2013-04-22
• Last Update Posted: 2013-04-23

Recruitment & Eligibility

• Status: TERMINATED
• Sex: Female
• Target Recruitment: 23

Inclusion Criteria

• women between the ages of 18 and 42
• election to preserve fertility by freezing eggs

Exclusion Criteria

• women over the age of 43
• patient unwilling to sign informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
oocyte freezing	vitrification of oocytes	includes any women who elects to preserve her fertility by vitrifying her unfertilized eggs.

Primary Outcome Measures

Name	Time	Method
Successful pregnancy	until the patient reaches 50 years of age	Eggs will be frozen via vitrification for those females electing to preserve their fertility; patients will return following an unspecified time period, when they are ready to use their frozen eggs. At that time, the eggs will be thawed and fertilized (with the sperm source of the participant's choice) to create embryos. This time frame will be unique to each individual; however, the Center has a policy whereby no embryo transfer will be performed beyond the age of fifty (50).

Secondary Outcome Measures

Name	Time	Method
oocyte survival	up to 50 years of age	the number of eggs that successfully survive the frozen-thawing procedure (vitrification).
fertilization	up to 50 years of age	to calculate the rate for the number of oocytes that are successfully fertilized (via ICSI) following survival of the frozen-thaw procedure.
blastocyst formation	up to 50 years of age	calculates the number of successfully fertilized embryos that grow into blastocysts (day 5 of culture), created from eggs that underwent and survived vitrification.
implantation	up to 50 years of age	to determine the implantation rate of embryos that were created from vitrified oocytes.

Trial Locations

Locations (1)

Center for Human Reproduction; 🇺🇸 Manhasset, New York, United States