跳至主要内容
临床试验/NCT03044340
NCT03044340已完成不适用

Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner

Fondation Hôpital Saint-Joseph1 个研究点 分布在 1 个国家目标入组 33 人开始时间: 2017年1月12日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
33
试验地点
1
主要终点
Assessment of Chlorine ion production change

研究概览

简要总结

Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve by crisis when the feet extremities become red hot and painful. There are several types of EM but this study concern the adult primitive form. For a long time, the physiopathology was not described but now we know that there is a vascular form, with microcirculatory dysfunction and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography. Thermotest, a medical device which measure the thermic sensitivity is used to quantify neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions detect small nervous fiber in diabetic patients with good correlation with Thermotest.

The purpose of this study is to analyze the vascular side and the neurologic side on patients consulting for Erythromelalgy.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Pain with burn feeling at hands and feet extremities
  • •Crisis activated by the heat
  • •Age > 18 years old

排除标准

  • •Patients who had burn in extremities

研究组 & 干预措施

erythermalgia patient

Experimental

patient will be measured chlorine ions impedance with the SUDOSCAN and evaluation on pain du to temperature with the THERMOTEST

干预措施: impedance measurement and pain evaluation (Other)

结局指标

主要结局

Assessment of Chlorine ion production change

时间窗: Day1

patient will be measured the impedance of chlorinates ions by Sudoscan

Assessment of Temperature changing sensitivity

时间窗: Day1

Patients will be measured their sensitivity to temperature changing using the Thermotest

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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