Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Assessment of Chlorine ion production change
研究概览
简要总结
Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve by crisis when the feet extremities become red hot and painful. There are several types of EM but this study concern the adult primitive form. For a long time, the physiopathology was not described but now we know that there is a vascular form, with microcirculatory dysfunction and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography. Thermotest, a medical device which measure the thermic sensitivity is used to quantify neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions detect small nervous fiber in diabetic patients with good correlation with Thermotest.
The purpose of this study is to analyze the vascular side and the neurologic side on patients consulting for Erythromelalgy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pain with burn feeling at hands and feet extremities
- •Crisis activated by the heat
- •Age > 18 years old
排除标准
- •Patients who had burn in extremities
研究组 & 干预措施
erythermalgia patient
patient will be measured chlorine ions impedance with the SUDOSCAN and evaluation on pain du to temperature with the THERMOTEST
干预措施: impedance measurement and pain evaluation (Other)
结局指标
主要结局
Assessment of Chlorine ion production change
时间窗: Day1
patient will be measured the impedance of chlorinates ions by Sudoscan
Assessment of Temperature changing sensitivity
时间窗: Day1
Patients will be measured their sensitivity to temperature changing using the Thermotest
次要结局
未报告次要终点
