Comparative Study Between Safety and Effectiveness of High Versus Low Power HOLEP
- Conditions
- Benign Prostatic Hyperplasia
- Interventions
- Procedure: HOLEP for treating BPH
- Registration Number
- NCT05678452
- Lead Sponsor
- Al-Azhar University
- Brief Summary
Holmium laser enucleation (HOLEP) has became a standard of treatment of large prostates that indicates surgery. HOLEP is widely used nowadays. Many settings are used but no optimal setting was world wide adopted. The aim of this trial is to assess the Low-power Holmium laser enucleation of the prostate (LP-HoLEP)and compare to high-power (HP-HoLEP) for enucleation efficiency pertaining to the advantages of lower cost and minimal postoperative dysuria, storage symptoms, and negative sexual impact.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Male
- Target Recruitment
- 200
- large prostate indicated for surgical intervention.
- prostate cancer
- recurrent adenomas
- associated neurologic factors that may affect outcomes (e.g., neurogenic bladder)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description LP-HoLEP HOLEP for treating BPH 2J/25Hz setting HP-HoLEP. HOLEP for treating BPH 2J/50Hz setting
- Primary Outcome Measures
Name Time Method Enucleation Efficiency 3 hours Enucleated weight/min will be evaluated.
- Secondary Outcome Measures
Name Time Method The complications of both techniques 3 months The complications will be classified according to the modified Clavien classification system.
Dysuria will be assessed by dysuria visual analog scale 2 weeks burning micturation after the procedure. Dysuria will be assessed by dysuria visual analog scale
Trial Locations
- Locations (1)
Urology department - AlAzhar university
🇪🇬Cairo, Egypt