MedPath

Comparison of tofacitinib with NCES versus NCES alone for vitiligo

Phase 3
Conditions
Health Condition 1: O- Medical and SurgicalHealth Condition 2: L80- Vitiligo
Registration Number
CTRI/2024/01/061532
Lead Sponsor
All India Institute of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Adult ( >18 years) patients with non-segmental (generalized, acrofacial, focal) vitiligo clinically stable for <1 (3-12 months) year (VIDA Score +1 or +2)

Exclusion Criteria

1.Children, pregnant or lactating women with vitiligo

2.Patients with segmental vitiligo

3.Patients with vitiligo of clinical disease stability >1 year (VIDA score 0 or -1)

4.Patients with vitiligo of clinical disease stability < 3 months (VIDA score +3 or +4)

5.Patients with keloidal or bleeding tendency

6.Patients on topical treatment for last 2 weeks, and on phototherapy/systemic treatment for last 4 weeks

7.Patients with active tuberculosis / other systemic infection or any other contra-indication to tofacitinib

8.Patients with latent tuberculosis, who refuse prophylactic anti-tubercular treatment (Patients who have evidence of latent TB may be enrolled if they complete at least 4 weeks of appropriate treatment prior to randomization and agree to complete the remainder of treatment while in the trial)

9.Vitiligo patch <2.5cm2 or >100cm2

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath