Autism and Glutamatergic Synapse : Research of Genetic Mutations and Identification of Clinical and Neurophysiological Markers.

University Hospital, Tours4 sites in 1 country497 target enrollmentJanuary 2009

ConditionsAutism

Overview

Phase: N/A
Intervention: Not specified
Conditions: Autism
Sponsor: University Hospital, Tours
Enrollment: 497
Locations: 4
Primary Endpoint: screening of about 50 genes encoding proteins of the NMDA receptor complex, chosen according to their chromosomal localisation located in hotspots depicted by genome-wide screens in large population of autistic patients
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Neurophysiological, Molecular and Developmental Analysis of the glutamate synapse in Autism

Detailed Description

Analysis about 50 genes in glutamate synapse

Registry

clinicaltrials.gov

Start Date

January 2009

End Date

June 2014

Last Updated

9 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University Hospital, Tours

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•have a Pervasive Developmental Disorder

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

screening of about 50 genes encoding proteins of the NMDA receptor complex, chosen according to their chromosomal localisation located in hotspots depicted by genome-wide screens in large population of autistic patients

Time Frame: two years