Neurophysiological Molecular and Developmental Analysis of the Glutamate Synapse in Autism

Not Applicable

Completed

• Conditions: Autism

• Registration Number: NCT01770548
• Lead Sponsor: University Hospital, Tours

Brief Summary

Neurophysiological, Molecular and Developmental Analysis of the glutamate synapse in Autism

Detailed Description

Analysis about 50 genes in glutamate synapse

Study Timeline

• Study Start: 2009-01
• Primary Completion: 2011-01
• Study First Submitted: 2013-01-15
• Study First Submitted QC: 2013-01-16
• Study First Posted: 2013-01-17
• Study Completion: 2014-06
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-13
• Last Update Posted: 2017-01-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 497

Inclusion Criteria

• have a Pervasive Developmental Disorder

Exclusion Criteria

• N/A

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
screening of about 50 genes encoding proteins of the NMDA receptor complex, chosen according to their chromosomal localisation located in hotspots depicted by genome-wide screens in large population of autistic patients	two years

Trial Locations

Locations (4)

CHRU - Centre de Ressources Autisme (CRA); 🇫🇷 Brest, France

CHS du ROUVRAY; 🇫🇷 Rouen, France

Chru - Cic; 🇫🇷 Tours, France

CHRU - Pédopsychiatrie; 🇫🇷 Tours, France