The Conus Brugada Syndrome Study
Completed
- Conditions
- Brugada Syndrome
- Registration Number
- NCT06653504
- Lead Sponsor
- Barts & The London NHS Trust
- Brief Summary
An observational, analytical, cross sectional study investigating the effects of Conus branch and Right Ventricular (RV) Branch occlusion on surface ECG and intra-cardiac electrograms in patients undergoing percutaneous coronary intervention (PCI).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 3
Inclusion Criteria
- Aged 18-85
- Patients able and willing to give their written informed consent.
- Planned PCI of a CTO of a right coronary artery
- Planned use of an anchor balloon in the Conus branch or RV branch
Exclusion Criteria
- Patients considered unsuitable to participate by the research team (e.g., due to medical reasons, laboratory abnormalities, or subject's unwillingness to comply with all study related procedures).
- Patients with a pre-existing, confirmed or possible diagnosis of Brugada Syndrome
- Marked ST elevation or J point elevation on baseline (prior to procedure) ECG in the precordial leads (V1-V3)
- Pregnancy. This will be tested by urine HcG measurement
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ECG and/or electrogram changes During Procedure Incidence of ECG changes resembling a Brugada type 1 pattern of coved ST elevation (one of the three Brugada types) specifically significant J point elevation in the precordial leads (V1-V3) and/or electrogram changes on the epicardial and/or endocardial intracardiac traces which will then be compared for differences and evidence of a transmural voltage gradient existing between them.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Barts Health NHS Trust
🇬🇧London, United Kingdom
Barts Health NHS Trust🇬🇧London, United Kingdom