The effect of bee propolis in reducing the aphthous ulcers
Not Applicable
- Conditions
- k00-k14Recurrent Aphthous Stomatitis.k12.0
- Registration Number
- IRCT2013072214101N1
- Lead Sponsor
- Oral and Maxillofacial Diseases Research Center of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
1 - confirmed the clinical diagnosis of minor aphthous ulcers.
2 - At least once a month aphthous ulcer recurrence .
3 - a minimum interval of 2 weeks of previous treatment
4 - spontaneous healing wounds less than 2-1 weeks.
Exclusion criteria:
1 - Patients with anemia (based on the trial CBC (H1) and the hematologist), blood disorders.
2 - Lack of patient's satisfaction.
3 - Patients who are pregnant, lactating, under 8 years old and disabled.
4–usage of drugs that may affect the immune system.
5- allergy to propolis.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The frequency of recurrent aphthous stomatitis. Timepoint: monthly. Method of measurement: mean number of recurrence during a month.
- Secondary Outcome Measures
Name Time Method Mean size of ulcers. Timepoint: Biweekly. Method of measurement: By caliper.;Pain of ulcers. Timepoint: Biweekly. Method of measurement: VAS system.;Time of healing. Timepoint: Biweekly. Method of measurement: mean number of days of healing of ulcers.