A randomized, double-blind, parallel-group study to evaluate the effect of alkalized lidocaine on hemodynamic changes during tracheal intubation.
Not Applicable
- Conditions
- Patients who undergo surgeries under general anesthesia.
- Registration Number
- JPRN-UMIN000021563
- Lead Sponsor
- Department of Anesthesiology and Resuscitology, Shinshu University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with anticipated difficult airway, patients who scheduled for surgery with nasotracheal intubation, patients who were pretreated with beta-blockers, patients who scheduled for surgery with epidural anesthesia, spinal anesthesia or nerve block in addition to general anesthesia, pregnant or lactating women, and paients who are allergic to local anesthetics.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in blood pressure and heart rate during tracheal intubation.
- Secondary Outcome Measures
Name Time Method The degree of sore throat assessed by using a visual analogue scale (VAS, 0-100 mm) and hoarseness, dysphonea, nausea and vomitting are systematically evaluated as present or absent just after and at 15 minutes and 24 hours after extubation.