Fistula-associated Anal Adenocarcinoma - a Twenty Years' Single-center Experience.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,004
- 主要终点
- fistula-associated anal adenocarcinoma (FAAC)
研究概览
简要总结
The fistula-associated anal adenocarcinoma is rare in patients suffering from anal fistulas. There is only little data available for this patient collective making characterization and management of this disease difficult. Late diagnosis and advanced tumor stage at diagnosis result in poor clinical outcome. It is the purpose of this study to evaluate patients clinically diagnosed with a FAAC and to further perform a histopathological characterization of the available tumor specimen.
详细描述
All patients receiving surgery for an anal fistula in the years 1999 to 2019 at a tertiary university referral hospital were included in the analysis. A retrospective review of patients' charts was performed. Patients suffering from FAAC were eligible for histopathological analysis including immunohistochemistry and molecular profiling.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •anal fistula
排除标准
- •previous cancer of the anal canal
结局指标
主要结局
fistula-associated anal adenocarcinoma (FAAC)
时间窗: 1999-2019
include and analyze all patients suffering from FAAC
次要结局
未报告次要终点
研究者
Felix Harpain
Dr.med.univ.
Medical University of Vienna
