跳至主要内容
临床试验/NCT05381324
NCT05381324已完成不适用

Fistula-associated Anal Adenocarcinoma - a Twenty Years' Single-center Experience.

Medical University of Vienna0 个研究点目标入组 1,004 人开始时间: 1999年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,004
主要终点
fistula-associated anal adenocarcinoma (FAAC)

研究概览

简要总结

The fistula-associated anal adenocarcinoma is rare in patients suffering from anal fistulas. There is only little data available for this patient collective making characterization and management of this disease difficult. Late diagnosis and advanced tumor stage at diagnosis result in poor clinical outcome. It is the purpose of this study to evaluate patients clinically diagnosed with a FAAC and to further perform a histopathological characterization of the available tumor specimen.

详细描述

All patients receiving surgery for an anal fistula in the years 1999 to 2019 at a tertiary university referral hospital were included in the analysis. A retrospective review of patients' charts was performed. Patients suffering from FAAC were eligible for histopathological analysis including immunohistochemistry and molecular profiling.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • anal fistula

排除标准

  • previous cancer of the anal canal

结局指标

主要结局

fistula-associated anal adenocarcinoma (FAAC)

时间窗: 1999-2019

include and analyze all patients suffering from FAAC

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Felix Harpain

Dr.med.univ.

Medical University of Vienna

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