MSCT Angiography in Bleeding

Not Applicable

• Conditions: Lower Gastrointestinal Bleeding
• Interventions: Device: Multislice CT Angiography

• Registration Number: NCT03464513
• Lead Sponsor: Assiut University

Brief Summary

Lower gastrointestinal bleeding occurs distal to the ligament of treitz and may involve the small bowel, colon and rectum .

Active lower gastrointestinal bleeding is a common, potentially life threatening medical presentation that can be challenging to localize and treat .

There are many diseases that may cause lower gastrointestinal bleeding, including angiodysplasia, diverticulosis, benign or malignant bowel neoplasm, inflammatory bowel disease, ischemic bowel disease, and infectious bowel disease.

Often, gastrointestinal bleeding will stop spontaneously, but in approximately 25% of patients, bleeding is massive or recurrent, requiring imaging localization and directed therapy.

Detailed Description

Accurate and prompt diagnosis of the bleeding source is crucial because mortality can be as high as 40%if there is hemodynamic instability in patients .

Because of the length of GI tract, the multitude of pathologic processes that can result in GI bleeding, imaging plays a primary role in the diagnosis .

Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of localising the source of bleeding, especially in patients with continuous bleeding .

MSCTA is being increasingly used because it is a widely available, non-invasive and fast diagnostic technique that allows for the visualization of the entire intestinal tract and its lesions, the identification of the vascularity and possible vascular abnormalities. In addition, this technique does not require preparation in patients with acute bleeding.

Study Timeline

• Study First Submitted: 2018-02-23
• Status Verified: 2018-03
• Study First Submitted QC: 2018-03-07
• Last Update Submitted: 2018-03-07
• Study First Posted: 2018-03-14
• Last Update Posted: 2018-03-14
• Study Start: 2018-04-01
• Primary Completion: 2019-04-01
• Study Completion: 2020-04-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Patients presenting to assiut university hospital with active lower gastrointestinal bleeding.

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Exclusion Criteria

• Patients whom are sensitive to contrast. Pregnant women. Patients with renal insufficiency

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Patients with GIT bleeding	Multislice CT Angiography	Patients with active lower Gastrointestinal bleeding

Primary Outcome Measures

Name	Time	Method
MSCTA in the evaluation of patients presenting with active lower gastrointestinal bleeding.	1 hour	Multislice ct angiography