The effect of betamethasone cream in preventing radiation skin reaction in head and neck cancers
Phase 3
- Conditions
- Health Condition 1: null- Patients getting Radical Radiotherapy in Head and Neck malignancies
- Registration Number
- CTRI/2017/04/008298
- Lead Sponsor
- Dr Shyama Prem S
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
Patients should be recieving radical RT,With ECOG 1&2
Exclusion Criteria
Previously irradiated,connective tissue disorder,allergy to cream
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method efficacy of 0.1% Topical Betamethasone cream in decreasing the proportion of patients with Grade 2,3,4 radiation dermatitis in Head and Neck malignanciesTimepoint: from start of radiotherapy to 2 weeks following completion
- Secondary Outcome Measures
Name Time Method To assess patientsâ?? skin related quality of life using EORTC QLQ-H&N 35 quality of life scores <br/ ><br>Timepoint: At start of treatment and completion of treatment;To assess toxicities of topical application of 0.1% Betamethasone cream. <br/ ><br>Timepoint: From start of radiotherapy to 2 weeks following completion;To evaluate 0.1% Topical Betamethasone cream as an interventional agent in Radiation dermatitis based on time to develop grade 2,3,4 dermatitis <br/ ><br> <br/ ><br>Timepoint: from start of radiotherapy to 2 weeks following completion