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Zmax Pediatric Vs Adult Concentration For The Treatment Of Acute Otitis Media

Phase 3
Completed
Conditions
Otitis Media
Registration Number
NCT00360100
Lead Sponsor
Pfizer
Brief Summary

Assess tolerability of different dosing formulations (adult versus pediatric).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
120
Inclusion Criteria
  • Have clinical signs/symptoms of AOM in at least 1 ear
Exclusion Criteria
  • Known or suspected hypersensitivity, or intolerance to azithromycin or other macrolides or to any penicillin, beta-lactam antibiotic or beta lactamase inhibitor
  • Previously diagnosed disease(s) of immune function
  • Treatment with any systemic (intravenous, intramuscular, oral) antibiotic for any indication within 7 days prior to enrollment

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Treatment-related vomiting on Day 1, which is based directly on the collected observed or voluntarily reported vomiting.
Secondary Outcome Measures
NameTimeMethod
Investigator and Sponsor assessment of clinical response.
Time-to-vomiting (in minutes) will be measured for all vomiting episodes that occur within the 60-minute observation period post-dosing on Day 1.
Frequency of the number of days of treatment-related vomiting by treatment group for subjects in the All Treated population.
Frequencies of occurrence, by day, of treatment-related vomiting.

Trial Locations

Locations (1)

Pfizer Investigational Site

🇵🇦

Ciudad de Panama, Panama

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