Improving Parkinson's related overactive bladder

Not Applicable

Completed

• Conditions: Specialty: Dementias and neurodegeneration, Primary sub-specialty: Parkinson's Disease; UKCRC code/ Disease: Neurological/ Other degenerative diseases of the nervous system; Nervous System Diseases; Parkinson's Disease

• Registration Number: ISRCTN13217913
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust

Brief Summary

2020 results in https://www.ncbi.nlm.nih.gov/pubmed/32054791 (added 17/02/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-05-15
• Study Completion: 2018-04-04
• Last Update Posted: 3 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

1. Idiopathic Parkinson's disease
2. Urinary symptoms defined as one or more of the following:
2.1. Urinary frequency (need to pass urine 7 or more times during the day)
2.2. Urgency: A sudden compelling desire to pass urine which is difficult to defer accessed
2.3. Urge incontinence : involuntary leakage of urine accompanied by/ or immediately preceded by urgency
2.4. Mixed urinary incontinence: involuntary leakage associated with urgency and also with exertion, effort, sneezing or coughing. Where clinically urge incontinence is the major component
2.5. Over active bladder: urgency combined with frequency or nocturia (need to pass urine one or more times a night)

Exclusion Criteria

1. Dementia such that they cannot follow training program or a Montreal Cognitive Assessment Score <24
2. Indwelling catheter
3. Renal failure requiring dialysis
4. Congestive cardiac failure requiring diuretic therapy
5. Current urinary tract infection confirmed by on microscopy
6. Completed bladder training in the last 12 months
7. Known prostate cancer or clinical evidence of this conditions
8. Uncontrolled bladder outlet obstruction / BPH
9. Pelvic organ prolapse past the vaginal introits
10. Known bladder malignancy or persistent haematuria on dipstick
11. Urinary retention >200ml on post void bladder scan
12. Previous Urogynecological Surgery for incontinence
12. Poorly controlled diabetes

Study & Design

• Study Type: Interventional
• Study Design: Not specified