Comparison of the effect of dexmedetomedine and remifentanil in reducing paranasal sinus surgery bleeding
Phase 3
- Conditions
- Bleeding during paranasal sinus surgery.
- Registration Number
- IRCT20220222054094N1
- Lead Sponsor
- Sanandaj University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Age 18 to 45 years
Patient in class 1 or 2 ASA physical status
Patients who have referred for para-nasal sinus surgery, septoplasty and rhinoplasty
Exclusion Criteria
History of heart disease, hypertension, kidney, liver and lung and blood coagulation disorders
History of mental health problems
Patients receiving anti-hypertensive drugs
Patients receiving NSAIDs
Patients with a BMI greater than 30
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding. Timepoint: Intervals of 15 minutes during surgery. Method of measurement: The amount of bleeding during the operation will be recorded based on the surgeon's comments and according to the quality of the surgical field, as well as the amount of bleeding based on the 5-point Likert scale in 15-minute intervals during the surgery.Score 1: Uncontrolled bleeding, Score 2: Severe bleeding, surgical field is distorted immediately after suction, Score 3: Moderate bleeding, frequent suction required, vision in the surgical field is moderate,Score 4: Minor bleeding, occasional suction required, vision in the surgical field is good,Score 5: No bleeding in the surgical field, almost bloodless. The amount of blood sucked in the suction bottle will also be measured (by calculating the amount of serum used for washing and reducing it from the total volume). Blood gases will also be weighed at the end of the operation using a heat scale.
- Secondary Outcome Measures
Name Time Method Pain. Timepoint: Recovery period and every 2 hours to 6 hours after the recovery period. Method of measurement: Using the Visual Analogue Scale (VAS), which is a numerical scoring scale (zero painless to 10 highest pain), based on patient's statement.;Vital sign (Mean arterial pressure, heart rate and SPo2). Timepoint: Mean arterial pressure, heart rate and SPo2 will be recorded at 1 minute after intubation and then every 5 minutes to half an hour and then every 15 minutes until the end of the syrgery. It will also be measured at 15 minute intervals during the recovery period. Method of measurement: Patient bedside monitoring device(Non invasive blood pressure, Pulse oximetry ).;Sedation - Agitation. Timepoint: At Recovery period. Method of measurement: Using the 7-point sedation-Agitation Scale (Riker).