KCT0000077
Recruiting
未知
Comparative Study on the Efficacy and Safety of Initial Combination Therapy of Low Dose Propiverine Hydrocholoride Compared to Alpha-antagonist Monotherapy in men with BPH with Overactive bladder: A Prospective Placebo Controlled Study
ConditionsDiseases of The genitoruinary system
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of The genitoruinary system
- Sponsor
- Inha University Hospital
- Enrollment
- 236
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. signed Informed consent form
- •2\. Male aged more than 45
- •3\. IPSS more than 12
- •4\. Enlarged prostate on DRE
- •5\. Symptoms of urinary urgency with voiding 3/day
- •6\. Symptoms of urinary frequency (8 micturitions per 24 hours)
- •7\. Symptoms of LUTS more than 3 months
- •8\. understanding and agreed the purpose of trial
Exclusion Criteria
- •1\. Total daily urine volume of \> 3000 ml
- •2\. Initial RU more than 150ml
- •3\. Significant hepatic or renal disease
- •(twice the upper limit of the reference ranges for serum concentrations of AST \[SGOT], ALT \[SGPT], alkaline phosphatase or creatinine)
- •4\. Any condition that is a contraindication for anticholinergic treatment, including uncontrolled narrow\-angled glaucoma, urinary retention or gastric retention
- •5\. Symptomatic acute urinary tract infection (UTI) during the run\-in period
- •6\. Recurrent UTIs defined as having been treated for symptomatic UTIs \> 4 times in the last year
- •7\. Diagnosed or suspected interstitial cystitis
- •8\. Clinically significant hematuria or hematuria secondary to malignant disease.
- •9\. PSA more than 10ng/dl (can include PSA between 4 and 10 if biopsy is negative)
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Comparative study of the efficacy and safety of intranasal ketamine and midazolam for the acute treatment of migraine with prolonged auraMigraineNervous System DiseasesISRCTN18446134Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)30
Not yet recruiting
Not Applicable
Safety and efficacy of Intrathecal Morphine as an Analgesic in Post-operative Total Knee ReplacementHealth Condition 1: M170- Bilateral primary osteoarthritis of kneeHealth Condition 2: O- Medical and SurgicalCTRI/2021/05/033462Dr Dipak Desai
Not yet recruiting
Phase 4
comparing the efficacy and safety ofintralesional acyclovir in two concentration in common wartsHealth Condition 1: L088- Other specified local infections of the skin and subcutaneous tissueCTRI/2024/02/063057Dr RPGMC Kangra at Tanda
Completed
Phase 1
The effect of ajicoat and cadaver on burn treatmentIRCT20190807044468N1Esfahan University of Medical Sciences50
Not yet recruiting
Phase 3
Topic Oleozon in patients with epidermophytosisEpidermophytosisTineaDermatomycosesMycosesSkin Diseases, InfectiousSkin DiseasesSkin and Connective Tissue DiseasesBacterial Infections and MycosesInfectionRPCEC00000289ational Center For Scientific Research300