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Clinical Trials/NCT00506818
NCT00506818
Completed
Not Applicable

Cognitive and Emotional Impairment After Stroke

Sykehuset Asker og Baerum1 site in 1 country250 target enrollmentFebruary 2007

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Sykehuset Asker og Baerum
Enrollment
250
Locations
1
Primary Endpoint
Effects of vascular risk-factor-intervention on changes in TMTA, ten-words-test and HAD
Status
Completed
Last Updated
16 years ago

Overview

Brief Summary

Cognitive and emotional symptoms are often seen in the acute phase of a stroke. The prevalence of such symptoms later and the mechanisms explaining the symptoms are not fully known. The causes of poststroke dementia are likely to be multifactorial (Cerebrovascular Diseases 2006). The investigators want to include all patients with first ever stroke without significant cognitive decline prior to the stroke (IQCODE cut-off 3,7) and follow them up for one year. At baseline we will make stroke classifications, measure neurological deficits according to NIHSS, evaluate cognitive and emotional function and make registrations of vascular risk factors, including precerebral color duplex scan with measurement of IMT in CCA. The investigators will then randomize the patients into multifactorial vascular-risk-factor-intervention in the hospital or care as usual in the primary health care. 8-12 months after stroke onset, survivors will undergo new examinations to evaluate neurological, cognitive and emotional functions, as well as MRI and SPECT.

Registry
clinicaltrials.gov
Start Date
February 2007
End Date
June 2009
Last Updated
16 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Sykehuset Asker og Baerum

Eligibility Criteria

Inclusion Criteria

  • First ever stroke or TIA
  • No cognitive decline (IQCODE \< 3,7)
  • Survived the acute stroke
  • Expected to live at least for one year after stroke

Exclusion Criteria

  • Cognitive decline

Outcomes

Primary Outcomes

Effects of vascular risk-factor-intervention on changes in TMTA, ten-words-test and HAD

Time Frame: 8-12 months after stroke onset

Secondary Outcomes

  • Prevalence of dementia and depression after stroke(8-12 month after stroke onset)

Study Sites (1)

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