Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 4
- 主要终点
- To Prospectively Collect Data on Chest CT Screening for Patients at Increase Lung-cancer Risk After Hodgkin's Disease.
研究概览
简要总结
This research study is being done because patients with a history of chest radiation treatment for Hodgkin's disease have been shown to be at increased risk for developing lung cancer a number of years out from treatment. The risk appears to be further increased among patients with a smoking history. Currently, the practice is to recommend annual low-dose chest CT scans in survivors of Hodgkin's disease who have received prior chest radiation treatment and who have at least a moderate smoking history. In this study, the CT scans will be read and interpreted by the study radiologist, and the results recorded in a consistent manner.
详细描述
- Participants will undergo a chest computed tomography (CT) scan once a year for a 3-year period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •5 years or longer from initial Hodgkin's disease diagnosis
- •Current age 18 or older
- •Received mediastinal irradiation and/or alkylating-agent based chemotherapy
- •Smoking history of 10-pack years or more, or current smoker
- •Pre-approval from the participant's insurance company for the CT study
排除标准
- •Patients with a history of lung cancer
- •Currently receiving treatment for another cancer diagnosis
- •Known diagnosis of any metastatic cancer
- •Pregnant women
结局指标
主要结局
To Prospectively Collect Data on Chest CT Screening for Patients at Increase Lung-cancer Risk After Hodgkin's Disease.
时间窗: 3 years
In this study, patients will under annual low-dose chest CT screening. The total number of lung cancer detected through the screening will be recorded
次要结局
未报告次要终点
研究者
Andrea K. Ng, MD
Radiation Oncologist
Dana-Farber Cancer Institute