A Cross-sectional Study of Venous Thromboembolism Risk Profiles and Prophylaxis in Neurosurgical Inpatients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9,010
- 试验地点
- 1
- 主要终点
- Rate of VTE occurrence
研究概览
简要总结
Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients. VTE has been estimated an incidence ranged from 79 per 100000 to 269 per 100000 population1. The incidence of VTE rises up to 3.0% in average among all postoperative neurosurgical patients in recent studies, but the number varies in a large range according to primary diseases. This cross-sectional study was aimed to investigate the incidence, associated risk factors, prophylaxis, treatment, and outcomes of VTE in a large clinical neurosurgery center in China.
详细描述
Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients. This cross-sectional study was aimed to investigate the incidence, associated risk factors, prophylaxis, treatment, and outcomes of VTE in a large clinical neurosurgery center in China. 9010 patients underwent neurosurgery procedure were included. Distribution of age, sex, whether received PICC during perioperative period, and some special primary diseases are significantly different between VTE and non-VTE patients. Student's test and chi-square test were performed for analyses. We investigated VTE incidence, risk factors, prophylaxes, treatment and outcomes in postoperative neurosurgical patients, and summarized the VTE susceptible population of the patients, providing a VTE patient profile for neurosurgeons to concern.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Neurosurgical Inpatients. Underwent neurosurgery procedure.
排除标准
- •Acute or chronic respiratory failure. Acute myocardial infarction or other serious heart diseases.
结局指标
主要结局
Rate of VTE occurrence
时间窗: 19 months
VTE incidence in postoperative neurosurgical patients during inhospital time from Jun 1,2018 to Dec 31,2019
次要结局
- Rate of complete vessel recanalization(19 months)
- Rate of bleeding events(19 months)
- Rate of partial vessel recanalization rate(19 months)
研究者
Shengqing Li
Chief Physician,Professor
Huashan Hospital