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临床试验/CTRI/2025/06/088042
CTRI/2025/06/088042尚未招募不适用

Comparative evalutaion of silver diamine fluoride penetration into dentine with three different application techniques using scanning electron microscope- energy dispersive x-ray spectroscopy an ex-vivo study

Dr Julita Joseph1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年6月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
SDF increases the resistance to acid dissolution and increases mineral density and hardness. A rich mineralised layer can be found on the surface of arrested carious lesions.Applying KI with SDF creates a silver iodide precipitate that is yellow, insoluble and does not cause black staining on the tooth

研究概览

简要总结

This is a comparative study done to evaluate the amount of silver ions in carious lesions in tooth treated with silver diamine fluoride, silver diamine fluoride followed by potassium iodide and silver diamine fluoride with light curing for 20 seconds. SDF increases the resistance to acid dissolution andincreases mineral density and hardness. A rich mineralised layer can be foundon the surface of arrested carious lesions. It also exhibits controlof caries infection, simplicity of use, affordability, minimal requirement fortraining and it is a minimally invasive treatment. Potassium iodide(KI) is a salt that generates white or transparent hexahedral crystals.Applying KI with SDF creates a silver iodide precipitate that is yellow,insoluble and does not cause black staining on the tooth. It is seen that curingof SDF using light emitting diode (LED) light curing increased precipitation ofsilver ions in the infected dentine layer of the carious lesion.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
8.00 Year(s) 至 13.00 Year(s)(—)
性别
All

入选标准

  • Freshly extracted carious primary teeth that are nearing exfoliation.
  • Primary teeth with visible dentinal caries.

排除标准

  • Primary teeth with caries involving pulp.
  • Primary teeth previously treated with SDF(silver diamine fluoride).
  • Primary teeth with restorations.
  • Primary teeth with developmental anomalies.

结局指标

主要结局

SDF increases the resistance to acid dissolution and increases mineral density and hardness. A rich mineralised layer can be found on the surface of arrested carious lesions.Applying KI with SDF creates a silver iodide precipitate that is yellow, insoluble and does not cause black staining on the tooth

时间窗: Silver penetration at 1min, after 2min and after 20seconds

次要结局

  • Efficiency of SDF when applied alone and when applied with potassium iodide and light curing.(Efficiency of SDF when applied alone and when applied with potassium iodide and light curing.)

研究者

发起方
Dr Julita Joseph
申办方类型
Other [self]

研究点 (1)

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