Effectiveness of Peer Navigation and Contingency Management on Retention in HIV Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 579
- 试验地点
- 12
- 主要终点
- Change in HIV RNA viral load suppression and medication adherence over 12 months
研究概览
简要总结
Consistent treatment with anti-retroviral therapy (ART) suppresses viral load (VL), prolonging life and improving quality of life for HIV+ persons. Suppressing VL benefits communities by reducing transmission to others. Mere availability of ART and care, however, is insufficient; the benefits of ART depend upon HIV+ persons' continuous visits to the health care provider, regular monitoring and regular delivery of medications, - known as retention in HIV care. In spite of national efforts, up to a quarter of HIV+ persons, especially low-income minorities are out of care. Innovative interventions are therefore urgently needed to maximize engagement and retention in HIV care, self-reported adherence, as well as HIV-1 RNA viral load suppression. In pursuit of these aims, the proposed study will assess outcomes of the following interventions in comparison to usual care: 1) contingency management (CM) only; 2) peer navigation (PN) only; and 3) a combined approach that integrates both CM and PN (CA) which the investigators hypothesize to be most effective in improving HIV clinical outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed HIV+
- •Age 18 years or older
- •English or Spanish speaking
- •Residence in Los Angeles County
- •prescribed ART in prior 24 months
- •< 3 visits in prior 12 months or have detectable viral load, as identified in the Ryan White CaseWatch database
排除标准
- •Not meeting any of the criteria identified above
结局指标
主要结局
Change in HIV RNA viral load suppression and medication adherence over 12 months
时间窗: Basline, follow-ups at month 2, and 12
Using the same design, to examine the effects of the PN, CM and, CA interventions on HIV RNA viral load suppression and self-reported adherence
Change in retention-in-care behaviors over 12 months
时间窗: Basline, follow-ups at month 2, 6, 12
Using a 2x2 factorial design, to examine the effect of the three interventions -- peer navigation, contingency management, combined approach and usual care -- and evaluate how well they improve retention in HIV care
次要结局
- Cost effectiveness(5 years)