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Clinical Trials/NCT02310893
NCT02310893
Completed
Not Applicable

Effectiveness of Peer Navigation and Contingency Management on Retention in HIV Care

University of California, Los Angeles6 sites in 1 country579 target enrollmentJanuary 2016
ConditionsHIV/AIDS

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
HIV/AIDS
Sponsor
University of California, Los Angeles
Enrollment
579
Locations
6
Primary Endpoint
Change in HIV RNA viral load suppression and medication adherence over 12 months
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Consistent treatment with anti-retroviral therapy (ART) suppresses viral load (VL), prolonging life and improving quality of life for HIV+ persons. Suppressing VL benefits communities by reducing transmission to others. Mere availability of ART and care, however, is insufficient; the benefits of ART depend upon HIV+ persons' continuous visits to the health care provider, regular monitoring and regular delivery of medications, - known as retention in HIV care. In spite of national efforts, up to a quarter of HIV+ persons, especially low-income minorities are out of care. Innovative interventions are therefore urgently needed to maximize engagement and retention in HIV care, self-reported adherence, as well as HIV-1 RNA viral load suppression. In pursuit of these aims, the proposed study will assess outcomes of the following interventions in comparison to usual care: 1) contingency management (CM) only; 2) peer navigation (PN) only; and 3) a combined approach that integrates both CM and PN (CA) which the investigators hypothesize to be most effective in improving HIV clinical outcomes.

Registry
clinicaltrials.gov
Start Date
January 2016
End Date
January 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosed HIV+
  • Age 18 years or older
  • English or Spanish speaking
  • Residence in Los Angeles County
  • prescribed ART in prior 24 months
  • \< 3 visits in prior 12 months or have detectable viral load, as identified in the Ryan White CaseWatch database

Exclusion Criteria

  • Not meeting any of the criteria identified above

Outcomes

Primary Outcomes

Change in HIV RNA viral load suppression and medication adherence over 12 months

Time Frame: Basline, follow-ups at month 2, and 12

Using the same design, to examine the effects of the PN, CM and, CA interventions on HIV RNA viral load suppression and self-reported adherence

Change in retention-in-care behaviors over 12 months

Time Frame: Basline, follow-ups at month 2, 6, 12

Using a 2x2 factorial design, to examine the effect of the three interventions -- peer navigation, contingency management, combined approach and usual care -- and evaluate how well they improve retention in HIV care

Secondary Outcomes

  • Cost effectiveness(5 years)

Study Sites (6)

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