The Effect of Coconut Oil on Alopecia in Women Receiving Doxorubucin-Cycylophosphamide Treatment for Breast Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 86
- 试验地点
- 1
- 主要终点
- National Cancer Instute (NCI) Common Terminology Criteria for Adverse Events (CTCAE); Alopecia
研究概览
简要总结
İn this study will be conducted to evaluate the effect of coconut oil on alopecia in 86 female breast cancer patients treated at Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital between 01.02.2025-31.12.2025.
详细描述
Cancer is a disease in which the cells in our body multiply uncontrollably and develop by metastasizing, and the symptoms, course and consequences of the disease can show complex qualities in each patient. Cancer treatments have benefits and harms. One of these side effects is alopecia.
Alopecia due to cancer treatments is a condition of hair loss, partial or complete, usually temporary but rarely permanent.
In chemotherapy-induced alopecia, the hair follicle is damaged due to the pause in the anagen phase and causes the hair to break off spontaneously during activities such as washing and brushing the hair.
Various scales are used in the evaluation of alopecia due to cancer treatments, such as the National Cancer Institute Common Terminology Criteria for Side Effects and the Dean Alopecia Scale.
Some applications are made to prevent and treat alopecia. These include strategies and pharmacological applications to physically reduce the amount of medication given to the hair follicle.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
盲法说明
Patients with breast cancer in the experimental and control groups will be masked.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •• To have been diagnosed with breast cancer.
- •The chemotherapy treatment plan should be planned as the Doxorubicin-Cyclophosphamide protocol.
- •Volunteer to participate in the study.
- •Be 18 years of age or older.
- •Being a woman.
排除标准
- •• Having any health problem or disability that prevents communication (vision-hearing problems, neurological, psychiatric diseases).
- •Planning other treatments other than the Doxorubicin-Cyclophosphamide protocol for the treatment of breast cancer.
- •Not volunteering to participate in the study.
- •Having previously experienced any disease/skin problem that causes hair loss.
- •Having received chemotherapy before.
研究组 & 干预措施
Control Group
At the beginning of the study,patients will be asked to fill out an individual information form containing demographic information and disease process before the first chemotherapy application. Patients in the control group will be asked not to apply anything to their hair. In each subsequent week, the presence of hair loss of the patients will be evaluated with the alopecia evaluation scale.
Experimental group
At the beginning of the study,patients will be asked to fill out an individual information form containing demographic information and disease process before the first chemotherapy application.The coconut oil application protocol will be explained to the patients in the experimental group and 10 milliliters of coconut oil will be applied to the hair follicles once a week. Alopecia assessment will be done every week.
干预措施: Coconut Oil (Other)
结局指标
主要结局
National Cancer Instute (NCI) Common Terminology Criteria for Adverse Events (CTCAE); Alopecia
时间窗: 1-12 WEEK
Grade 1; Hair loss of \<50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage Grade 2; Hair loss of \>=50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact
次要结局
未报告次要终点
研究者
İsmail DAKDEVİR
Nurse
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital