Hybrid Intraprocedural Imaging From 2D-Strain-echocardiography and X-ray Based Biplane Coronary Angiography for Guiding Interventional Revascularization Therapy
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Cut-Off-Value of vital myocardial tissue
研究概览
简要总结
The investigators will check the feasibility of an intraprocedural vitality diagnostics and the identification of an indication for Percutaneous transluminal coronary angioplasty (PTCA).
详细描述
After myocard vitality diagnostics with MRI patients will underwent additionally an stress echocardiography within the exploration. By this ultrasound we will measure the LV mass and the ejection fraction per apical 2-, 3- and 4-chamber view.
In addition a 2D-strain-analysis will be done to measure the systolic and diastolic strain and also the circumferential and radial strain rate parameter (by depicting three parasternal short axis views in the basal, mid-ventricular and apical plane).
These measurements will be compared with the studies-conditioned MRI-finding (as reference) to find the optimal strain-parameter and the optimal cut-off-data for an intraprocedural vitality diagnostics of the single layers (endocardial, myocardial, and epicardial) for this patient group.
The data upraised through this are compared off-line to the MRI findings.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •left ventricular wall motion abnormalities
- •existent myocardial vitality MRI exploration
- •reduced LV-function
- •steady angina pectoris
- •patients which are legally competent and which are mentally able to understand the study staff
- •patients give their written consent
排除标准
- •pregnancy or lactation
- •acute or instable angina pectoris
- •acute myocardial infraction in the last 3 month
研究组 & 干预措施
2D-strain echo
After myocard vitality diagnostics with MRI follows a stress echocardiography to determine the LV volumes and EF. The received Data are compare with the MRI-Data(reference)to identify the ideal strain-parameters and Cut-Off-Result for an intraprocedural vitality diagnostic of the different films (endocardial, myocardial and epicardial).
干预措施: 2D-strain echo (Procedure)
结局指标
主要结局
Cut-Off-Value of vital myocardial tissue
时间窗: time during hospitalization
It will be determine cutt-off-value of vital myocardial tissue in comparison to MRI myocardial vitality findings.
次要结局
- feasibility and safety of echocardiography during catheter investigations(time during hospitalization and 1 months afterwards)
- Determination of Strain-Parameter for identification of vital myocardial tissue(time during hospitalization)