A clinical trial to study the effect of two drugs, dexamethasone and dexmedetomidine given as a regional anesthesia in patients undergoing surgeries for forearm and hand.

Not yet recruiting

• Conditions: Bursopathy, unspecified, (2) ICD-10 Condition: M200||Deformity of finger(s), (3) ICD-10 Condition: M849||Disorder of continuity of bone, unspecified, (4) ICD-10 Condition: M674||Ganglion, (5) ICD-10 Condition: L99||Other disorders of skin and subcutaneous tissue in diseases classified elsewhere, (6) ICD-10 Condition: M679||Unspecified disorder of synovium and tendon,

• Registration Number: CTRI/2022/09/045450
• Lead Sponsor: MANIPAL HOSPITAL BANGALORE

Brief Summary

THE AIM OF THE STUDY IS TO COMPARE THE EFFICACY OF ADDING DEXAMETHASONE AND DEXMEDETOMIDINE AS ADJUVANTS TO 0.5% ROPIVACAINE IN REDUCING THE ONSET AND EXTENDING THE DURATION OF AXILLARY BLOCK AND ALSO TO COMPARE THE PAIN SCORE AND POST OPERATIVE ANALGESIC REQUIREMENT.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-14
• Last Update Posted: 2022-12-09

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

ASA 1 & 2 ELECTIVE ELBOW, FOREARM, WRIST AND HAND SURGERIES UNDER AXILLARY BRACHIAL PLEXUS BLOCK.

Exclusion Criteria

ALLERGY TO DRUGS USED IN THE STUDY HISTORY OF LONGTERM OPIOIDS OR OTHER ANALGESIC CONSUMPTIONS PATIENTS ON SYSTEMIC CORTICOSTEROIDS FOR 2WEEKS OR MORE WITHIN 6MONTHS OF SURGERY PATIENTS WITH BLEEDING OR COAGULATION DISORDERS PATINETS WITH ANY NEUROLOGICAL OR MUSCULOSKELETAL DISORDERS ANY CONTRAINDICATIONS FOR BLOCKS USED IN THE STUDY INFECTION OF LESION AT THE SITE OF THE BLOCK TECHNICAL FAILURE OF THE BLOCK PREGNANT PATIENTS, PATIENTS WITH HEART BLOCK, HYPOTENSION, BRADYCARDIA, CARDIAC FAILURE.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TO FINDOUT WHETHER DEXAMETHASONE AND DEXMEDETOMIDINE WHEN COMBINED WITH 0.5% ROPIVACAINE PROLONG THE DURATION OF SENSORY AND MOTOR BLOCK	24HOURS

Secondary Outcome Measures

Name	Time	Method
EFFECT ON ONSET OF ACTION	24HOURS
EFFECT ON POST OPERATIVE ANALGESIC REQUIREMENTS	24HOURS
INCIDENCE OF BRADYCARDIA, HYPOTENSION AND ARRHYTHMIAS	24HOURS
EFFECT ON PATIENT SATISFACTION	24HOURS

Trial Locations

Locations (1)

MANIPAL HOSPITAL WHITEFIELD; 🇮🇳 Bangalore, KARNATAKA, India

MANIPAL HOSPITAL WHITEFIELD

🇮🇳Bangalore, KARNATAKA, India

SHIVANANDA N V

Principal investigator

9686585584

shivananda.nadiminti@gmail.com