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Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals

Not Applicable
Completed
Conditions
Spider Fear
Arachnophobia
Interventions
Behavioral: Exposure
Behavioral: occasional aversive imagination
Registration Number
NCT05424250
Lead Sponsor
Philipps University Marburg Medical Center
Brief Summary

The effectiveness of an optimized extinction training is investigated in spider-fearful individuals. Participants will undergo a one-session standardized extinction training, either with or without occasional metal imagination of most feared apprehension towards spiders. The effectiveness of the training is measured by symptom improvement according to subjective ratings and behavioural avoidance tests one week later.

Detailed Description

The present study aims to investigate the applicability of an optimized exposure training using imagination. Exposure training is an effective approach to the treatment of various anxiety disorders. However, there are a significant number of patients who do not benefit or who develop anxiety following successful treatment. The process of extinction underlying exposure is the focus of current research on optimizing exposure. In this regard, one promising approach for improving extinction learning involves the occasional presentation of fear-generating stimuli (unconditioned stimuli \[US\]; often an electrical stimulus in experimental studies) during extinction (occasional reinforced extinction, ORE). Previous experimental studies provide preliminary evidence for a less pronounced return of fear after extinction training with occasional presentation of the US. In clinical practice, this strategy is recommended to optimize extinction learning in the treatment of individuals with anxiety. However, the transfer of the procedure used (real presentation of an unconditioned stimulus) into clinical practice seems difficult to realize. One way to facilitate the transfer of the ORE approach into clinical practice could be the use of vivid imagination of a personally relevant fear-generating situation during extinction training/exposure (e.g., patients' central concerns). Therefore, the aim of the present study is to examine the applicability of ORE using imagination. In this context, a standardized extinction training either with or without mental imagination of a personally relevant fear situation (e.g., central concern of the consequences when confronted with spiders) will be performed in individuals with spider-fearful individuals. The approach used for individuals with spider fear is well established and has been successfully implemented in previous studies by instructed trainers (e.g., individuals with a bachelor's degree in psychology). The aim of this randomized controlled trial in healthy individuals with increased fear of spiders is to investigate whether optimized extinction training (extinction training + imagination) is more effective in reducing fear of spiders in the long term compared to standard extinction training.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
67
Inclusion Criteria
  • Elevated score on Spider Phobia Questionnaire (SPQ) > 17
Exclusion Criteria
  • Severe allergies to bees/spiders/insects
  • current psychotherapeutic/psychiatric treatment
  • past psychotherapeutic/psychiatric treatment due to anxiety problems
  • current or past psychotic symptoms
  • current suicidal intent
  • experience with exposure-based treatment
  • current psychopharmacological medication
  • severe cardiovascular, respiratory or neurological diseases

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ExposureExposureStandard extinction training with seven standardized exposure steps
Exposure + occasional aversive imaginationExposurerepeated imaginations of the participants' most feared apprehension during extinction training with seven standardized exposure steps
Exposure + occasional aversive imaginationoccasional aversive imaginationrepeated imaginations of the participants' most feared apprehension during extinction training with seven standardized exposure steps
Primary Outcome Measures
NameTimeMethod
Spider Phobia Questionnaire (SPQ)Change from baseline to post-treatment (i.e., 7-9 days)

31-item true/false questionnaire assessing symptoms of arachnophobia. Scores range from 0 to 31, with greater scores representing greater fear of spiders. Spider phobic individuals have obtained mean scores of 23.20 (SD = 2.90) and 23.76 (SD = 3.80) on the SPQ.

Fear ratingChange from baseline to post-treatment (i.e., 7-9 days)

Maximum fear rating on a scale from 0 (no fear) to 100 (severe fear) recorded once during BAT

Behavioral Approach Test (BAT)Change from baseline to post-treatment (i.e., 7-9 days)

Number of test steps fully completed (0-14 steps)

Secondary Outcome Measures
NameTimeMethod
Change in anxiety sensitivity (ASI-3)change from baseline to post-treatment (i.e. 7-9 days)

The Anxiety Sensitivity Index (ASI-3) is a self-report measure of fear of anxiety-related body symptoms (i.e., anxiety sensitivity). Total score range: 0 to 72. Higher scores indicate worse anxiety sensitivity.

Fear of Spider Questionnaire (FSQ)Change from baseline to post-treatment (i.e., 7-9 days)

14-item questionnaire on a 7-point Likert scale (0 = 'I don't agree at all'; 6 = 'I completely agree') assessing symptoms of arachnophobia. Total score range: 0 to 84. Higher scores indicate worse severity of arachnophobia.

US expectancy and fear ratingsBaseline

Ratings of US expectancy and fear during exposure training on a scale from 0 (I don't expect my feared outcome/I am not scared at this moment) to 100 (I completely expect my feared outcome to happen/I am severely scared at this moment). Specifically, we asked participants to rate their US expectancy and fear before and during each of the 27 trials.

PROMIS Emotional Distress-Anxiety-Short Formchange from baseline to post-treatment (i.e. 7-9 days)

The DSM-5-TR Level 2-Anxiety-Adult measure is the 7-item PROMIS Anxiety Short Form that assesses the pure domain of anxiety in individuals age 18 and older. Each item on the measure is rated on a 5-point scale (1=never; 2=rarely; 3=sometimes; 4=often; and 5=always) with a range in score from 7 to 35 with higher scores indicating greater severity of anxiety.

Trial Locations

Locations (1)

Philipps-University Marburg

🇩🇪

Marburg, Hesse, Germany

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