Pancreatic Adenocarcinoma Gene Environment Risk Study

Recruiting

• Conditions: Pancreatic Cancer

• Registration Number: NCT00912717
• Lead Sponsor: University of Pittsburgh

Brief Summary

After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Some participants may also be asked to provide a urine sample. Individuals undergoing procedures that require collection of biological samples for clinical purposes may have these samples saved for research purposes. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical and family histories. Data and biospecimens will be stored for potential future research projects.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-01
• Study First Submitted: 2009-06-01
• Study First Submitted QC: 2009-06-02
• Study First Posted: 2009-06-03
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-10
• Last Update Posted: 2024-10-14
• Primary Completion: 2027-12
• Study Completion: 2027-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

• Histologically confirmed or CT confirmed diagnosis of pancreatic adenocarcinoma
• Subjects with abnormal imaging study (CT, MRI, MRCP, EUS)
• Control subjects with a clinical diagnosis of a pancreas, liver, or intestinal condition
• Control subject with acute pancreatitis
• Control subject with chronic pancreatitis
• Control subject with biliary obstruction
• Control subject with pancreatic cyst
• Member of a high risk family (≥ 1 close relative with pancreatic cancer)
• Healthy control (without any of the above conditions)

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Exclusion Criteria

• Under the age of 18 years
• Unable to give informed consent
• Inability to travel to Pittsburgh for in-person enrollment

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The data will be used in cohort association studies. Endpoints will depend on the number of patients in the study and the number of markers that are being evaluated.	10 years

Trial Locations

Locations (1)

University of Pittsburgh; 🇺🇸 Pittsburgh, Pennsylvania, United States