Breath-Hold in Abdominal & Lung Cancer Radiotherapy - Tumour Reproducibility, Tumour Stability & Patient Experience

Not Applicable

• Conditions: ung Cancer; Liver Cancer; Kidney Cancer; Pancreatic Cancer; Adrenal Gland Cancer; Lung Cancer; Cancer - Lung - Non small cell; Cancer - Kidney; Cancer - Pancreatic; Cancer - Liver

• Registration Number: ACTRN12618001691235
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-10-12
• Study Completion: 2020-04-27
• Last Update Posted: 22 June 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

1. Eligible for standard fractionated or SABR treatment to liver, kidney, adrenal, pancreas or lung (SABR only) per standard departmental policy
2. Informed consent
3. Aged >18 years
4. English speaking, or able to follow instructions in English
5. Eligible for breath-hold technique based on radiation oncologist assessment. Considerations may include but are not limited to:
a) Patient able to voluntarily hold their breath for greater than 15 seconds when comfortably seated
b) Patient of good performance status, ECOG 0-2
c) Patient able to lay in treatment position for greater than 45 minutes

Exclusion Criteria

1. Unable to consent/withdrawal of consent/decline consent
2. Non-English Speaking or unable to follow spoken English instructions
3. Ineligible for any breath-hold technique based on radiation oncologist assessment & criteria outlined in study methods

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To measure the reproducibility of tumour position (or its surrogate) between each breath hold in inhale, deep-inhale and exhale, measured using kV fluoroscopy.[At time of test];2. To measure the stability of tumour position (or its surrogate) during each breath hold in inhale, deep-inhale and exhale breath-hold, measured using kV fluoroscopy. [At time of test];3. To measure the inter-fraction and intra-fraction reproducibility of tumour position at treatment delivery, measured on Cone Beam Computed Tomography (CBCT)[At time of test]