An Experimental And Clinical Pilot Study To Evaluate The Antispasmodic Effect Of Alcoholic Extract Of Bhrahmi(Bacopa Monnieri) Capsule In Abdominal Colic.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- assessment of reduction of abdominal pain after 24 hours
研究概览
简要总结
Abdominal colicky pain is very frequently seen in many surgical conditions likes urinary Calculus, hepato-colicky, intestinal colicky pain, abdominal cramps, dysmenorrhoea. Abdominal pain is that you feel anywhere between your chest and groin. This is often referred to as the stomach region or belly. Main differential diagnosis of abdominal pain could be urinary calculus, appendicitis, Cholecystitis, Bowel obstruction, Pancreatitis, Chronic functional abdominal pain, Constipation. Most of the pain can be seen as spasmodic pain as there is smooth muscle spasm. In Ayurved there is no specific word for spasmodic pain but abdominal pains are referred as udarshula that most of the time is colicky in nature. One such very painful condition referred as if pain experienced as if death. Pain given by yama (God of death). Antispasmodic drugs used in modern science in the form of oral, intravenous & intramuscular drugs in the abdominal colic, but frequent use of NSAIDS & Antispasmodic drugs may lead to complications due to their ill effect like chronic kidney disease and moreover in chronic kidney disease the more use of analgesic drugs are contraindicated. Ayurvedic medications with shoolhara properties are mentioned in the ashmari chikitsa and Udarshula rogadhikar like Brahmi, sunthi, trivrut, haritak,etc are mentioned in samhitas.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •Patient having age in between 18 to 80 years.
- •Patient with abdominal colicky pain without needing of immediate surgical intervention.
- •Patients with Multiple urinary calculi (unilateral or bilateral), Cholecystitis and Cholelithiasis, abdominal cramps, hepato colicky pain, dysmenorrhoea.
- •Patient of both genders taken irrespective of caste, religion, and socio-economic status.
排除标准
- •Renal or Ureteric Calculus with severe Hydronephrosis.
- •Obstructive renal calculi with severe infection.
- •Obstructive jaundice.
- •Patient who needs immediate surgical intervention like complete bowel obstruction.
- •Chronic systemic illness like malignancy & positive HIV, HBSAG, HCV.
结局指标
主要结局
assessment of reduction of abdominal pain after 24 hours
时间窗: 24 hours
次要结局
- assessment of pain after giving medication 3 hours, 6 hours, 12 hours(3,6 and 12 hours)
