Detection and treatment of endobronchial (pre-)malignant lesions after treatment of early stage lung cancer in COPD patients

• Conditions: Lung cancer; 10029107

• Registration Number: NL-OMON35775
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 890

Inclusion Criteria

T1N0M0 or T2aN0M0 histologically proven NSCLC with a maximum tumor diameter of 4cm, treated with either anatomical surgical resection or SBRT with curative intent within the last six months. T descriptors according to the 7th edition of the TNM classification for lung cancer. ;GOLD II-IV COPD prior to resection.10

Exclusion Criteria

Adjuvant chemo-, immune- or radiotherapy
Current or recent (<5 years) cancer other than lung cancer.
Chronic respiratory failure, defined as PaO2 <60 mmHg with or without PaCO2 >50 mmHg.10

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Five-year cancer free survival<br /><br><br /><br></p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Overall five-year survival<br /><br>Quality of life<br /><br>Cost-effectiveness</p><br>