Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor
Not Applicable
Recruiting
- Conditions
- Heart failure
- Registration Number
- JPRN-jRCT1030230386
- Lead Sponsor
- Obokata Masaru
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 220
Inclusion Criteria
1) Patients equal or more than 50 years age
2) Patients with heart failure
3) Patients with a baseline MoCA-J score < 26 (regardless of the cause of dementia)
4) Patients who have given written informed consent to participate in the study
Exclusion Criteria
1) Patients with severe dementia for whom MoCA-J is difficult to perform
2) Patients who require palliative care
3) Patients with comorbidities for which a prognosis of at least 1 year is not expected (other than heart failure)
4) Patients participating in other interventional trials
5) Other patients who are judged by the physician to be inappropriate for inclusion in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in MoCA-J from baseline to 12 months after intervention
- Secondary Outcome Measures
Name Time Method Change in Hippocampal Volume from baseline to 12 months after intervention<br>Change in cerebral white matter lesions from baseline to 12 months after intervention<br>Change in cerebral gray matter volume from baseline to 12 Months after intervention<br>Change in KCCQ-12 from baseline to 12 months after intervention<br>Change in NT-proBNP from baseline to 12 months after intervention<br>Change in E/e' from baseline to 12 months after iIntervention<br>Change in left atrial volume from baseline to 12 months after intervention