跳至主要内容
临床试验/CTRI/2025/03/083564
CTRI/2025/03/083564招募中2/3 期

A randomised clinical study to evaluate add on effect of patol yush as an aahariya kalpana over mustadikwath ghanwati in the management of sthaulya with special reference to obesity.

Shivani Bapusaheb Jassud1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年4月7日最近更新:

试验速览

阶段
2/3 期
状态
招募中
发起方
入组人数
60
试验地点
1
主要终点
To assess the add on effect of patol yush over mustadikwath ghanawati in sthoulya with special reference to obesity.

研究概览

简要总结

The main aim of Ayurveda is to cure diseases and maintain a state of health. Ayurveda focuses on maintaining and restoring the body’s ability to balance itself and fight ailments. Obesity is a chronic, complex disease defined by excessive fat deposits that can impair health. It increases the risk of type 2 diabetes, heart disease, and can affect bone health, reproduction, and the risk of certain cancers. Obesity also impacts the quality of life, including sleep and movement.

Overweight and obesity are the fifth leading cause of global deaths. According to the World Health Organization (WHO) in 2022, 2.5 billion adults aged 18 years and older were overweight, including over 890 million adults living with obesity. The prevalence of Sthaulya (obesity) is increasing worldwide across all age groups. According to Ayurvedic texts, Sthaulya is a Santarpanjanya Vyadhi and is detailed in the Ashtang Hridaya and Charak Samhita. In obesity, the Medovaha Strotas (fat channels) are affected, leading to the overgrowth of Medodhatu (fat tissue), which ultimately manifests as obesity.

Weight gain occurs due to an imbalance between energy intake and energy expenditure. According to Acharya Charaka, continuous intake of causative factors aggravates Kaphadosha and Medodhatu due to their similar properties. This increases the obstruction of Meda in the channels, and as a result, Vata in the digestive system becomes hyperactive. This stimulates Agni (digestive fire), causing rapid digestion of food and leading to frequent hunger. If sufficient food is not available, this imbalance can cause severe complications.

Ayurveda emphasizes the importance of proper nutrition through appropriate food choices, combinations, and cooking methods. Medohara and Kaphanashana diets are recommended in Ayurveda for managing Sthaulya (obesity). Patol Yush is mentioned in the Sushrut Samhita as an effective remedy for treating Medoroga (obesity). It possesses properties such as reducing Kapha, eliminating excess fat, improving digestion, and supporting heart health. This study aims to evaluate the combined effect of Patol Yush as an Aahariya Kalpana (dietary formulation) with Mustadikwath Ghanwati in managing Sthaulya, as Mustadikwath Ghanwati has already shown effectiveness in treating obesity.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • 1.Age group between 18 to 50 years irrespective of gender, caste and religion.
  • 2.BMI 25 to 39.9kg per meter square 3.Subjects showing classical signs and symptoms of Sthaulya like Dourbalya, Swedaatipravruti, Dourghandhya, Nidraadhikya, Kshudhaadhiikya and Pipasa adhikya.

排除标准

  • 1.Pregnant women 2.Lactating mother 3.Subjects with long term steroid treatment.
  • 4.Subjects having comorbidities like DM, cardiovascular diseases, cancers etc.

结局指标

主要结局

To assess the add on effect of patol yush over mustadikwath ghanawati in sthoulya with special reference to obesity.

时间窗: 5 weeks | Follow up every week

次要结局

  • 1.To observe the add on effect of patol yush over mustadikwath ghanwati on BMI, waist hip ratio over period of 5 weeks.(2.To observe the add on effect of patol yush over mustadikwath ghanwati on lipid profile over period of 5 weeks.)

研究者

发起方
Shivani Bapusaheb Jassud
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Shivani Bapusaheb Jasud

R. A. Podar Medical (Ayu.) College, Worli, 400018

研究点 (1)

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