Preoperative tramadol combined with diclofenac sodium reduces intraoperative loading dose of tramadol in patients undergoing abdominal hysterectomy
Completed
- Conditions
- Postoperative painAnaesthesiology - Anaesthetics
- Registration Number
- ACTRN12614000391673
- Lead Sponsor
- Turkish Ministery of Health Ankara Etlik ZH Maternity and Women’s Health Research and Teaching Hospital, Ankara, Turkey
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 45
Inclusion Criteria
Elective Total Abdominal Hysterctomy with or without BSO under general anesthesia
Exclusion Criteria
Known allergy, sensitivity or contraindications to study drugs, inability to use PCA device, long-term use of opioid medications, use of any analgesic drugs in the last 24 hours, history of clinically significant cardiac, respiratory, hepatic or renal disease and history of chronic pain and previous history of postoperative nausea and vomiting.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tramadol-PCA consumption in the first 24 hours postoperatively[Postoperative 24 hours]
- Secondary Outcome Measures
Name Time Method Emergence time (time elapsed from the termination of anesthetic agents to gaining the ability of spontaneous eye opening, gripping fingers and breathing deeply on request) [Postoperative 24 hours];sedation score (alert,0; drowsy but rousable to voice,1; drowsy but rousable to shaking,2) [Postoperative 24 hours];postoperative nausea and vomiting [Postoperative 24 hours];Time to first activation of Patient Control Analgesia (PCA)(time elapsed from the administration of intraoperative loading dose) [Postoperative 24 hours];Verbal rating scale scores (Pain: none,0; mild,1; moderate,2; strong,3; unbearable,4)[Postoperative 24 hours];rescue analgesic medication[postoperative 24 hours]