The usage of unenriched emulsified fat transplant in temporomandibular joint degenerative diseases
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Collected radiological evaluations and questionnaires
研究概览
简要总结
The aim of this study is to determine the effectiveness of using nanofat in the treatment of temporomandibular joint osteoarthritis (TMJ OA). The study seeks to identify correlations between the patient's subjective symptoms, clinical presentation, and radiological findings, perform data analysis, and apply the results in clinical practice.
The hypothesis of this study is that the injection of autologous nanofat into the temporomandibular joint slows the progression of degenerative changes, promotes the regeneration of the deformed joint surface, and thereby improves the quality of life for patients.
入排标准
- 年龄范围
- 18 years 至 64 years（18-64 Years）
- 接受健康志愿者
- 否
入选标准
- •The study plans to include patients aged 18-65 years, with TMJ OA classified as stage 4 or 5 according to the Wilkes classification (9), and who have not responded to at least 6 months of conservative treatment. Participation in the study is voluntary, and the participant may withdraw at any stage.
排除标准
- •Exclusion criteria include pregnancy, severe chronic diseases (malignant tumors, lymphoproliferative disorders, coagulation disorders, diabetes, acute viral infections, and severe general health conditions), or prior surgical treatment of the temporomandibular joint.
结局指标
主要结局
Collected radiological evaluations and questionnaires
Collected radiological evaluations and questionnaires
次要结局
未报告次要终点
研究者
Oksana Ivask
Scientific
Tartu University Hospital