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临床试验/NCT05430451
NCT05430451进行中(未招募)不适用

Building Capacity and Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2022: Simple Physical Exercise With Instant Messaging Support for Smoking Cessation

The University of Hong Kong1 个研究点 分布在 1 个国家目标入组 1,031 人开始时间: 2022年6月18日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
1,031
试验地点
1
主要终点
Biochemically validated abstinence

研究概览

简要总结

This project aims to test the effectiveness of an integrated intervention of brief cessation advice (AWARD) and simple physical exercise with Instant Messaging (IM) support compared with control participants among current smokers who joined the contest.

详细描述

Although smoking prevalence is decreasing in Hong Kong, it accounts for over 7,000 deaths per year and a large amount of medical cost, long-term care, and productivity loss of US$ 688 million (0.6% Hong Kong GDP). Quitting is difficult because nicotine is highly addictive. Long-term habitual tobacco smoking could foster a series of physical and psychological dependence on nicotine, and thus induce cravings and nicotine withdrawal symptoms when remaining abstinent.

In addition to pharmacotherapy and behavioral counseling, exercise has shown promising effects on reducing craving, cigarette consumption, withdrawal symptoms, and increasing intention and attempt to quit. Randomized trials on smoking cessation have shown that vigorous or moderate exercise (including aerobics, brisk walking, and weightlifting) increases tobacco abstinence. However, these exercise-based smoking cessation trials were small-scaled with sample sizes ranging from 20 to 543, and mainly targeted the smokers who were motivated to quit (active treatment seekers). Most (15/20) of the vigorous or moderate exercises adopted in the smoking cessation trials required the participants to attend multiple exercise sessions (at least weekly for 5 months) under supervision or self-monitoring using equipment (e.g., pedometers) with a low proportion (<50%) of the participants achieved targeted level of attendance and exercise. The effects were short-term (end of treatment) and long-term (6 months or above) effects were uncertain, and cannot be generated in smokers who had low motivation to quit.

Mobile health (mHealth) is now a part of the World Health Organization's (WHO) strategies on combating smoking (http://www.who.int/tobacco/mhealth/en/) and has been used in many countries given its low cost and popular use. Instant messaging (IM) applications (apps) (e.g., WhatsApp, WeChat) are compatible with smartphones and allow sending interactive messages such as text, photos, video, animation, and files. The widespread availability of IM apps allows healthcare professionals to deliver health information and behavioral interventions through messaging. The QTW Contest 2017 using chat-based psychosocial support through IM apps effectively increased short-term (end of treatment, 3 months) and long-term (6 months since intervention initiation) smoking abstinence.

The chat-based IM support has the potential to support the use of other treatment components. The investigators aimed to test (1) the effectiveness of an integrated intervention of brief cessation advice (AWARD), simple physical exercise with Instant Messaging (IM) support compared with control participants among current smokers; (2) to explore participants' experience and perceptions towards the intervention.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Hong Kong residents aged 18 or above
  • Smoke at least 1 tobacco stick (includes HTP) per day or use e-cigarette daily in the preceding 3-month
  • Able to communicate in Chinese (including reading Chinese in IM)
  • Saliva cotinine 30 ng/ml or above
  • Intent to quit / reduce smoking
  • Able to use the instant messaging tool (e.g., WhatsApp, WeChat) for communication.

排除标准

  • Smokers who have communication barriers (either physically or cognitively)
  • Smokers who are currently participating in other SC programmes or services

结局指标

主要结局

Biochemically validated abstinence

时间窗: 6-month follow-up

Defined as exhaled CO level \<4ppm and saliva cotinine level ≤30 ng/ml

次要结局

  • Smoking reduction rate change from baseline at 3-month follow-up(3-month follow-up)
  • Intervention compliance at the end of treatment at 3 months follow-up(3-month follow-up)
  • Physical exercise level(6-month follow-up)
  • Smoking reduction rate change from baseline at 6-month follow-up(6-month follow-up)
  • Smoking quit rate change from baseline at 3-month follow-up(3-month follow-up)
  • Smoking quit rate change from baseline at 6-month follow-up(6-month follow-up)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Wang Man-Ping

Associate Professor

The University of Hong Kong

研究点 (1)

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